Evidence supporting the use of: Prebiotic blend (proprietary)
For the health condition: Allergies (respiratory)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Prebiotic blends—composed of non-digestible fibers such as inulin, fructooligosaccharides (FOS), and galactooligosaccharides (GOS)—are primarily known for supporting gut health by nourishing beneficial intestinal bacteria. Emerging scientific research suggests a possible connection between prebiotics and the modulation of immune responses, which may be relevant to respiratory allergies, such as allergic rhinitis and asthma. The gut microbiota is involved in the regulation of the immune system, and dysbiosis (an imbalance in gut bacteria) has been linked to increased susceptibility to allergic diseases.

Several animal studies and a limited number of human clinical trials have investigated the impact of prebiotic supplementation on allergic outcomes. Some studies suggest that prebiotics may help reduce the incidence or severity of allergic symptoms by promoting the growth of beneficial bacteria such as Bifidobacterium and Lactobacillus, which in turn may modulate immune responses and reduce inflammation. For example, research published in journals like Allergy and Clinical & Experimental Allergy has shown that prebiotic supplementation in infants can reduce the risk of developing allergic symptoms. However, the evidence in adults is less robust, and the effects are generally modest.

Overall, there is preliminary scientific evidence supporting the use of prebiotic blends to help modulate immune function and potentially reduce respiratory allergy symptoms, but the evidence is not strong or conclusive, especially for established allergies in adults. More high-quality, large-scale human trials are needed to confirm efficacy and clarify mechanisms.

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