Evidence supporting the use of: Vitamin C (mixed ascorbates)
For the health condition: Allergies (respiratory)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid or mixed ascorbates) has been investigated for its potential to support or treat respiratory allergies, including allergic rhinitis and asthma. The rationale for its use is primarily based on its antioxidant properties, ability to modulate immune function, and role in reducing histamine levels. Several small clinical studies and observational reports suggest that vitamin C supplementation may help decrease symptoms associated with respiratory allergies by reducing oxidative stress and inflammation in the airways. For example, some research has shown that vitamin C levels are lower in individuals with allergic diseases, and supplementation may modestly improve symptoms or reduce the severity of allergic responses.

However, the overall quality of evidence is limited. Most studies are small, heterogeneous in design, and often use vitamin C in combination with other interventions, making it difficult to attribute benefits to vitamin C alone. Systematic reviews and meta-analyses generally conclude that while there is biochemical plausibility and limited clinical support, the strength of evidence is weak and does not support routine use of vitamin C as a primary treatment for respiratory allergies. More rigorous, large-scale randomized controlled trials are needed to clarify its efficacy. Thus, while there is some scientific rationale and preliminary evidence, it is not robust, and vitamin C is not a standard therapy for respiratory allergies.

More about Vitamin C (mixed ascorbates)
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