Evidence supporting the use of: Cannabinoids
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cannabinoids, the active compounds found in cannabis, have been investigated for their potential role in supporting or treating Alzheimer's disease (AD). The scientific interest is based on preclinical studies that suggest cannabinoids may exert neuroprotective, anti-inflammatory, and anti-oxidative effects. Laboratory and animal studies have shown that cannabinoids like THC and CBD may reduce beta-amyloid plaque accumulation, promote neurogenesis, and modulate neuroinflammation, all of which are implicated in AD pathology. For example, some studies have demonstrated that THC can inhibit the aggregation of beta-amyloid proteins and decrease neuron death in cell cultures. Additionally, animal models suggest cannabinoids may improve behavioral symptoms such as agitation and aggression. However, the clinical evidence in humans is very limited and mostly consists of small-scale or preliminary trials. These studies have primarily focused on behavioral symptoms rather than disease modification, with modest benefits and notable side effects. Larger, well-controlled clinical trials are lacking, and cannabinoids are not currently approved as a treatment for Alzheimer's disease by major regulatory agencies. Therefore, while there is a scientific rationale and preliminary evidence, the overall quality and quantity of clinical evidence supporting cannabinoid use in Alzheimer's disease is limited, and its use remains investigational.

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Other ingredients used for Alzheimer's Disease

acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
l-carnosine
l-serine
l-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
sulforaphane glucosinolate
tocotrienols
trans-pterostilbene
tributyrin
ubiquinol
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vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
mulberry
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gastrodia
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lingzhi
morus
ferulic acid
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ganoderma
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terpene lactones
polyphenols
hypothalamus
herbal blend (proprietary)
algae
cocoa
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soy isoflavones
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7,8-Dihydroxyflavone
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Apigenin
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Benfotiamine
Basidiomycota
Brahmi
Bacopa
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bacoside
Baicalin
Caffeic Acid
Centrophenoxine
Camellia sinensis
Caryophyllene
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Crocin
Carnosine
Catalpol
Cyanidin
Curcuminoid
Curcumen
Chinese Ligustrum berry
Creatine
Curcuma
C-Phycocyanin
Convolvulus prostratus
Crocetin
Cytidine
Carnosic acid
Cannabigerol
Docosahexaenoic Acid
Decursin
Dihydrolipoic Acid
epicatechin
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Ergothioneine
Eicosapentaenoic Acid
Estrogen
Ecklonia
Flavonoids
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Products containing Cannabinoids

We currently have no products on Vitabase that contain this ingredient.