Evidence supporting the use of: Carotenoid
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Carotenoids are a class of naturally occurring pigments found in plants, and their antioxidant properties have led to research into their potential neuroprotective effects, including in Alzheimer's Disease (AD). Scientific interest is based on the role of oxidative stress in the pathogenesis of AD, where reactive oxygen species contribute to neuronal damage. Several epidemiological studies have found lower plasma levels of certain carotenoids (such as lutein, zeaxanthin, and beta-carotene) in patients with Alzheimer's compared to age-matched controls. Some observational studies suggest that higher dietary intake or blood levels of carotenoids may be associated with better cognitive function or a reduced risk of cognitive decline.

However, intervention trials and randomized controlled studies are limited and have produced mixed results. For example, supplementation with beta-carotene or mixed carotenoids has not consistently shown a significant effect in slowing cognitive decline or improving symptoms in AD patients. Most of the evidence remains observational, and causality has not been established. Thus, while there is a scientific rationale and some supporting data, the overall strength of evidence is weak, and carotenoids are not currently recommended as a primary or adjunctive treatment for Alzheimer's Disease.

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anthocyanins
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astaxanthin
berberine
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beta caryophyllene
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blueberry
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DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
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epigallocatechin gallate (EGCG)
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fish oil
fish protein
flavonols
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glycerophosphocholine (GPC)
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hesperetin
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l-carnitine
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l-serine
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lutein
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lycopene
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marine lipid
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melatonin
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niacinamide (vitamin B3)
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olive
omega-3 fatty acids
oyster mushroom
phenolic acids
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phosphatidylserine
phospholipids
phytocannabinoids
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Products containing Carotenoid

We currently have no products on Vitabase that contain this ingredient.