Evidence supporting the use of: Carotenoids
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Carotenoids, including lutein, zeaxanthin, and beta-carotene, are antioxidant compounds found in various fruits and vegetables. Their potential benefit in Alzheimer’s Disease (AD) is primarily based on their antioxidant and anti-inflammatory properties, which may protect neural tissue from oxidative stress—a key contributor to neurodegeneration in AD.

Several observational studies have found that individuals with AD tend to have lower levels of certain carotenoids in their blood and brain tissue. Some small-scale human studies and animal models suggest that dietary carotenoids may slow cognitive decline or improve certain cognitive functions. For example, lutein and zeaxanthin supplementation has shown modest benefits in cognitive performance in elderly populations, though these findings are not specific or robust for AD patients.

However, large, well-controlled clinical trials specifically evaluating carotenoid supplementation for the treatment or prevention of Alzheimer’s Disease are lacking. Meta-analyses and systematic reviews generally conclude that, while there is a biological rationale and some supporting observational data, the clinical evidence is limited and inconclusive. Thus, carotenoids are not a standard treatment for AD, but ongoing research explores their preventive potential.

In summary, while there is some scientific rationale and preliminary evidence for carotenoids in supporting cognitive health and possibly modifying the risk or progression of Alzheimer’s Disease, the strength of the evidence is low, and more rigorous studies are needed.

More about carotenoids
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Other ingredients used for Alzheimer's Disease

acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
l-carnosine
l-serine
l-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
sulforaphane glucosinolate
tocotrienols
trans-pterostilbene
tributyrin
ubiquinol
Urolithin A
vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
mulberry
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gastrodia
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lingzhi
morus
ferulic acid
cistanche
ganoderma
royal jelly
terpene lactones
polyphenols
hypothalamus
herbal blend (proprietary)
algae
cocoa
AMP-activated protein kinase (AMPK)
soy isoflavones
2-(carbamimidoyl-methyl-amino) ethoxyphosphonic acid
7,8-Dihydroxyflavone
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Apigenin
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Astragaloside
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Apocynin
Black Seed
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Baicalein
Benfotiamine
Basidiomycota
Brahmi
Bacopa
Bifidobacteria
bacoside
Baicalin
Caffeic Acid
Centrophenoxine
Camellia sinensis
Caryophyllene
Cinnamomum
Crocin
Carnosine
Catalpol
Cyanidin
Curcuminoid
Curcumen
Chinese Ligustrum berry
Creatine
Curcuma
C-Phycocyanin
Convolvulus prostratus
Crocetin
Cytidine
Carnosic acid
Cannabigerol
Docosahexaenoic Acid
Decursin
Dihydrolipoic Acid
epicatechin
Ellagic Acid
Ergothioneine
Eicosapentaenoic Acid
Estrogen
Ecklonia
Flavonoids
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Products containing carotenoids

We currently have no products on Vitabase that contain this ingredient.