Evidence supporting the use of: Cinnamon
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cinnamon has been investigated for its potential effects on Alzheimer's Disease (AD), primarily due to the presence of polyphenolic compounds such as cinnamaldehyde and epicatechin. Preclinical studies, particularly in vitro and animal models, have demonstrated that cinnamon extracts can inhibit the aggregation of tau proteins and amyloid-β plaques, which are hallmark features of AD pathology. Additionally, some studies suggest that cinnamon may possess neuroprotective, anti-inflammatory, and antioxidant properties, all of which could be beneficial in the context of neurodegenerative diseases.

Despite these promising laboratory results, there is a lack of robust clinical evidence to support the use of cinnamon in humans for the prevention or treatment of Alzheimer's Disease. Most of the data come from experimental studies, and only a few small-scale human trials have been conducted, none of which provide conclusive evidence for efficacy. There is also limited information about the appropriate dosage, safety, and long-term effects of cinnamon supplementation in this context.

In summary, while cinnamon shows scientific promise based on laboratory and animal studies, the current evidence in humans is insufficient. Further well-designed clinical trials are needed to determine whether cinnamon is an effective and safe intervention for Alzheimer's Disease.

More about cinnamon
More about Alzheimer's Disease

Other ingredients used for Alzheimer's Disease

2-(carbamimidoyl-methyl-amino) ethoxyphosphonic acid
7,14-Hydroxy-Docosapentaenoic Acid
7,8-Dihydroxyflavone
Acacetin
Acai berry
Acetyl L-carnitine
Acetylcholine
Agmatine
Akkermansia muciniphila
Algae
algal oil
alpha-linolenic acid (ALA)
alpha-lipoic acid
amentoflavone
amino acids
AMP-activated protein kinase (AMPK)
ampelopsin
aniracetam
anserine
anthocyanins
apigenin
apocynin
Aronia melanocarpa
ashwagandha
astaxanthin
astragaloside
avocado
Bacopa
Bacopin
bacoside
baicalein
baicalin
Basidiomycota
benfotiamine
berberine
beta caryophyllene
beta-hydroxybutyrate
Bifidobacteria
Bifidobacterium longum
bilobalide
black garlic
black seed
black tea
blueberry
brahmi
broccoli
butylphthalide
butyrate triglyceride
butyric acid
C-phycocyanin
caffeic Acid
caffeine
Camellia sinensis
cannabigerol
Cannabis sativa oil
caprylic acid
carnosic acid
Carnosine
caryophyllene
catalpol
catechins
centrophenoxine
Chinese Ligustrum berry
Chinese salvia root
chokeberry
choline
Cinnamomum
cinnamon
cistanche
citicoline
cocoa
coenzyme Q10 (CoQ10)
Convolvulus prostratus
creatine
crocetin
crocin
Curcuma
curcumen
curcumin
Curcuminoid
cyanidin
cyclodextrin
cytidine
d-alpha tocopherol
decursin
DHA (docosahexaenoic acid)
dihydrolipoic acid
docosahexaenoic Acid
DPA (docosapentaenoic acid)
Ecklonia
eicosapentaenoic acid
ellagic acid
EPA (eicosapentaenoic acid)
epicatechin
epigallocatechin gallate (EGCG)
ergothioneine
estrogen
fatty acids
ferulic acid
fisetin
fish
fish oil
fish protein
flavanols
flavanones
flavans
flavones
flavonoids
flavonols
flavonones
fo-ti
fungus
galantamine
gallate
gallic acid
gamma tocopherol
ganoderma
garcinol
gastrodia
gastrodin
genistein
ginkgetin
ginkgo biloba
ginkgo flavone glycoside
ginkgoheteroside
ginkgolides
Ginkgoside
ginseng
Ginsenosides
Glucoraphanin
glycerophosphocholine (GPC)
grape
green tea
Gypenoside
hemp
hemp oil
herbal blend (proprietary)
Hericenones
hericium mushroom
hesperetin
hesperidin
Homotaurine
Honokiol
huperzine A
hydroxytyrosol
Hyperoside
icariin
iridoids
isoliquiritigenin
isovitexin
Kaempferol
ketone salts
l-carnitine
L-carnosine
L-serine
L-theanine
Lentinula edodes mycelia
lingzhi
lion's mane
lipids
lutein
luteolin
Lycium
lycopene
magnesium
magnolol
malvidin
mangiferin
Marine fat
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Maslinic acid
Matcha
medium chain triglycerides (MCT)
Melatonin
Methoxylated flavones
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Morus
Mulberroside A
Mulberry
Myricetin
Myricitrin
N-acetyl-cysteine (NAC)
NADH
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Naringin
Nervonic acid
Niacinamide (vitamin B3)
nicotinamide riboside
Nigella seed
Nobiletin
Norvaline
Oleuropein
olive
omega-3 fatty acids
Osthole
oyster mushroom
paeoniflorin
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Peptides
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phosphatidylcholine
phosphatidylserine
phospholipids
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polygala root
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polyunsaturated fat
pomegranate
pregnenolone
punicalagins
Pycnogenol
pyrroloquinoline disodium salt
pyrroloquinoline quinone
quercetin
reishi mushroom
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rhizome
rosemary
rosmarinic acid
royal jelly
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selenium
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soy isoflavones
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sulforaphane glucosinolate
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turmeric
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ubiquinol
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Uridine
Urolithin A
Ursolic Acid
Vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
Walnut
Withanolides
Wogonin
Xanthohumol
Xanthophyll
Xylaria nigripes
β-nicotinamide mononucleotide (NMN)