Evidence supporting the use of: Curcuma
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Curcuma, especially in the form of Curcuma longa (turmeric), is used to support or treat Alzheimer’s Disease primarily based on scientific interest, though the evidence is limited and not yet conclusive. The main active compound in turmeric, curcumin, has demonstrated antioxidant, anti-inflammatory, and anti-amyloid properties in preclinical studies. In vitro and animal studies suggest that curcumin may help reduce amyloid plaque accumulation, oxidative stress, and neuroinflammation—key processes implicated in Alzheimer’s pathology.

However, clinical trials in humans have yielded mixed and generally disappointing results. Most studies report poor bioavailability of curcumin when taken orally, and no significant cognitive improvement has been consistently demonstrated in Alzheimer’s patients. Some small-scale trials report modest benefits on cognitive function or biomarkers, but these findings have not been replicated in larger, well-controlled studies.

While turmeric has a long history of use in traditional medicine for general cognitive and inflammatory conditions, its specific use for Alzheimer’s Disease is a more recent development driven by scientific research rather than long-standing tradition. Overall, while there is a scientific rationale and early-stage evidence, the current level of support is weak, and turmeric or curcumin is not considered a validated or standard treatment for Alzheimer’s Disease.

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alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
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butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
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chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
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ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
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l-serine
l-theanine
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lion's mane
lutein
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lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
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Chinese Ligustrum berry
Creatine
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Convolvulus prostratus
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Docosahexaenoic Acid
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epicatechin
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Products containing Curcuma

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