Evidence supporting the use of: Epigallocatechin
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Epigallocatechin, more commonly referenced as epigallocatechin gallate (EGCG), is a major catechin found in green tea. Its use in supporting or treating Alzheimer’s Disease (AD) is based on preclinical scientific evidence, but not yet on robust clinical validation in humans. Laboratory and animal studies have demonstrated that EGCG possesses antioxidant, anti-inflammatory, and neuroprotective properties, which may counteract some pathological mechanisms in AD, such as beta-amyloid aggregation, tau phosphorylation, and neuronal cell death. In vitro experiments suggest that EGCG can inhibit the formation of amyloid plaques and protect neurons from oxidative stress.

However, while these mechanistic findings are promising, clinical research is sparse. Only a few small-scale human studies and pilot trials have examined EGCG’s effects on cognitive function in patients with mild cognitive impairment or dementia, and results to date are inconclusive. Systematic reviews and meta-analyses highlight the need for larger, well-controlled clinical trials to establish efficacy and safety in AD patients. Thus, the evidence supporting EGCG’s use in Alzheimer’s Disease is preliminary and primarily based on preclinical research, not on direct clinical benefit in humans at this time.

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algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
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chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
L-carnosine
L-serine
L-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (Vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic compounds
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
sulforaphane glucosinolate
tocotrienols
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tributyrin
ubiquinol
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vinpocetine
vitamin B
vitamin B12
vitamin C
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vitamin E
mulberry
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gastrodia
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ganoderma
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hypothalamus
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Products containing Epigallocatechin

We currently have no products on Vitabase that contain this ingredient.