Evidence supporting the use of: Flammulina velutpies
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Flammulina velutipes, commonly known as enoki mushroom, has been studied for its potential neuroprotective properties, including possible benefits for Alzheimer's Disease (AD). Preclinical studies have identified several bioactive compounds in F. velutipes, such as polysaccharides, sterols, and antioxidants, which may exert neuroprotective effects through anti-inflammatory and antioxidant mechanisms. Some in vitro and animal studies suggest that extracts from this mushroom can inhibit acetylcholinesterase activity, reduce amyloid-beta aggregation, and improve cognitive function in AD models. For instance, a few rodent studies have reported improved memory and learning when treated with F. velutipes extracts, attributed to reduced oxidative stress and inflammation in the brain.

However, clinical evidence in humans remains limited. There are no large-scale, well-controlled clinical trials validating its efficacy or safety for Alzheimer's patients. Most available data are from preclinical research, which provides a promising but preliminary scientific basis. As such, while there is some scientific rationale and early evidence for F. velutipes' use in supporting cognitive health or AD, the level of evidence is low (rated 2/5), and its use cannot be considered a validated or standard treatment. Further research, particularly human clinical trials, is necessary to establish its effectiveness and safety for Alzheimer's disease.

More about Flammulina velutpies
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Products containing Flammulina velutpies

We currently have no products on Vitabase that contain this ingredient.