Evidence supporting the use of: Ginseng, Oriental
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Panax ginseng (Oriental ginseng) has a traditional history of use in East Asian medicine for enhancing cognitive function and vitality. In recent years, some scientific studies have investigated its potential benefits for Alzheimer's disease (AD). Preclinical research suggests that ginsenosides, the active compounds in ginseng, may exert neuroprotective effects, reduce oxidative stress, inhibit amyloid-beta aggregation, and modulate cholinergic neurotransmission—all mechanisms relevant to AD pathology.

Several small clinical trials have explored the effects of ginseng extracts in patients with Alzheimer's disease or mild cognitive impairment. Some of these studies report modest improvements in cognitive performance, particularly in memory and global cognitive scores, when compared to placebo. However, these trials often suffer from small sample sizes, short durations, and methodological limitations. Systematic reviews and meta-analyses generally conclude that while there is some evidence to suggest a potential benefit, the overall quality of evidence is low, and more rigorous, large-scale trials are needed to confirm efficacy and safety.

In summary, Panax ginseng is being studied for Alzheimer's disease with some promising preclinical and preliminary clinical findings. Nevertheless, the current scientific evidence is insufficient to recommend its use as a standard treatment, and further research is warranted.

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amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
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beta caryophyllene
bifidobacterium longum
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black tea
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citicoline
coenzyme Q10 (CoQ10)
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curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
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glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
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l-serine
l-theanine
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lutein
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lycopene
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marine lipid
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medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
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pomegranate
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Products containing Ginseng, Oriental

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