Evidence supporting the use of: Marijuana
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Marijuana (cannabis) has been investigated for its potential to support or treat symptoms of Alzheimer's Disease, primarily due to its active compounds, cannabinoids such as THC and CBD. The scientific interest is based on preclinical studies suggesting that cannabinoids may reduce neuroinflammation, oxidative stress, and amyloid-beta plaque accumulation—mechanisms implicated in Alzheimer's pathology. Animal models have shown that THC can reduce amyloid-beta levels and improve cognitive function. Moreover, cannabinoids may help manage behavioral symptoms in dementia, such as agitation and aggression, due to their anxiolytic and sedative properties.

However, human clinical evidence is limited and of low quality. A few small-scale clinical trials and observational studies have explored cannabis or cannabinoid use in Alzheimer's patients, mainly for symptom management (e.g., agitation, sleep disturbances), with mixed results. Some studies report modest improvements in behavioral symptoms, while others find no significant benefit and note potential adverse effects like sedation or confusion. There is insufficient evidence to conclude that marijuana or its components can halt or reverse the progression of Alzheimer's Disease itself.

In summary, while there is scientific rationale and some early evidence from laboratory and small clinical studies, robust clinical evidence in humans is lacking. Marijuana's use in Alzheimer's is thus supported by limited scientific validation, primarily for symptom control rather than disease modification.

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acai berry
acetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
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chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
l-carnosine
l-serine
l-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
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tocotrienols
trans-pterostilbene
tributyrin
ubiquinol
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vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
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bacoside
Baicalin
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Caryophyllene
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Crocin
Carnosine
Catalpol
Cyanidin
Curcuminoid
Curcumen
Chinese Ligustrum berry
Creatine
Curcuma
C-Phycocyanin
Convolvulus prostratus
Crocetin
Cytidine
Carnosic acid
Cannabigerol
Docosahexaenoic Acid
Decursin
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epicatechin
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Ergothioneine
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Estrogen
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Products containing Marijuana

We currently have no products on Vitabase that contain this ingredient.