Evidence supporting the use of: Olive Oil
For the health condition: Alzheimer's Disease

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Olive oil, particularly extra virgin olive oil (EVOO), has gained scientific interest for its potential role in supporting brain health and possibly reducing risk factors associated with Alzheimer’s Disease (AD). The Mediterranean diet, which is rich in olive oil, is epidemiologically linked with lower rates of cognitive decline and AD. Preclinical studies in animal models have shown that EVOO can reduce amyloid-beta plaque formation, neuroinflammation, and oxidative stress, all of which are implicated in AD pathogenesis. Notably, studies such as the PREDIMED trial and its sub-analyses reported that adherence to a Mediterranean diet supplemented with olive oil was associated with improved cognitive function compared to control diets. However, evidence from human clinical trials specifically targeting AD prevention or progression remains limited and mostly indirect. Most clinical studies are observational or involve dietary patterns rather than isolated olive oil supplementation. The bioactive compounds in olive oil, such as polyphenols (e.g., oleocanthal and hydroxytyrosol), are thought to exert neuroprotective effects, but definitive large-scale, randomized controlled trials in humans with established AD are lacking. In summary, while there is some scientific rationale and observational evidence that olive oil consumption may support brain health and potentially lower AD risk, the direct evidence for its use as a treatment or preventive agent for Alzheimer’s Disease in humans is modest. Thus, the evidence is rated as 2/5.

More about Olive Oil
More about Alzheimer's Disease

Other ingredients used for Alzheimer's Disease

Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
L-carnosine
L-serine
L-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (Vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic compounds
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
sulforaphane glucosinolate
tocotrienols
trans-pterostilbene
tributyrin
ubiquinol
Urolithin A
vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
mulberry
β-nicotinamide mononucleotide (NMN)
gastrodia
tinospora cordifolia
lingzhi
morus
ferulic acid
cistanche
ganoderma
royal jelly
terpene lactones
polyphenols
hypothalamus
herbal blend (proprietary)
Algae
cocoa
AMP-activated protein kinase (AMPK)
soy isoflavones
2-(carbamimidoyl-methyl-amino) ethoxyphosphonic acid
7,8-Dihydroxyflavone
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Aronia melanocarpa
Anserine
Avocado
Agmatine
Acetylcholine
Amentoflavone
Acacetin
Alpha-Lipoic Acid
Astragaloside
Ampelopsin
Aniracetam
Apocynin
Black Seed
Bilobalide
Butylphthalide
Beta-hydroxybutyrate
Bacopin
Baicalein
Benfotiamine
Basidiomycota
Brahmi
Bacopa
Bifidobacteria
bacoside
Baicalin
Caffeic Acid
Centrophenoxine
Camellia sinensis
Caryophyllene
Cinnamomum
Crocin
Carnosine
Catalpol
Cyanidin
Curcuminoid
Curcumen
Chinese Ligustrum berry
Creatine
Curcuma
C-Phycocyanin
Convolvulus prostratus
Crocetin
Cytidine
Carnosic acid
Cannabigerol
Docosahexaenoic Acid
Decursin
Dihydrolipoic Acid
epicatechin
Ellagic Acid
Ergothioneine
Eicosapentaenoic Acid
Estrogen
Ecklonia
Flavonoids
Fo-Ti
Fish
Fatty acids
Fungus
Flavanones
Flavans
Flavonones
Flavanols
Flavones
Gallic Acid
Ginsenosides
Garcinol
Ginkgetin
Galantamine
Gypenoside
Growth factors
Gallate
Ginkgolides
Ginkgo Flavone Glycoside
Ginkgoside
Ginkgoheteroside
Glucoraphanin
Gastrodin
Honokiol
Hyperoside
Hericenones
Hydroxytyrosol
Hericium mushroom
Hemp
Homotaurine
iridoids
isoliquiritigenin
Isovitexin
icariin
Kaempferol
Ketone Salts
Lycium
Lipids
Maslinic Acid
Methylcobalamin
Mangiferin
Mulberroside A
Myricitrin
Monoterpenes
Myricetin
Monounsaturated Fat
Malvidin
Marine fat
Methoxylated flavones
Magnolol
NADH
Norvaline
Naringenin
Nigella Seed
Nobiletin
Nervonic acid
Oleuropein
Osthole
Phycocyanin
Pyrroloquinoline Quinone
Piperine
Polysaccharides
Pentacyclic triterpenoids
Polydatin
Polyunsaturated Fat
Punicalagins
Paeoniflorin
Pycnogenol
Phytoestrogens
Polymethoxylated flavones
Polygala
Peptides
Rosmarinic Acid
Schizochytrium Oil
Solanaceae
Soy
Schizochytrium
Selenocysteine
Salmon Oil
Salidroside
Syringic acid
Shankhpushpi
Salvianolic acid
Shogaol
Schisandrins
Shilajit
Saffranal
S-allylcysteine
Sarcosine
Stilbenoid
Sulforaphane
Terpenoids
Tumerone
Taxifolin
Triterpenes
Tangeretin
trehalose
Taurine
Theaflavin
Turmerones
Tremella
Uncaria
Ursolic Acid
Uridine
Withanolides
Wogonin
walnut
Xanthohumol
Xanthophyll
Xylaria nigripes

Products containing Olive Oil

We currently have no products on Vitabase that contain this ingredient.