Evidence supporting the use of: Omega Blend
For the health condition: Alzheimer's Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Omega Blend supplements typically contain a mixture of omega-3 and sometimes omega-6 fatty acids, such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), which are found in fish oil and other sources. The rationale for using omega fatty acids in Alzheimer's disease (AD) stems from their known roles in neuronal membrane function, anti-inflammatory effects, and potential neuroprotective properties.
Several observational studies have linked higher dietary intake of omega-3 fatty acids with a reduced risk of cognitive decline and Alzheimer's disease. Some randomized controlled trials (RCTs) have examined omega-3 supplementation in patients with AD or mild cognitive impairment. However, the results have been mixed; while some studies report modest slowing of cognitive decline, especially in early or mild cases, others find no significant benefit. The 2020 Cochrane review concluded there is insufficient evidence to support omega-3 supplementation for preventing or treating dementia or cognitive decline in people who already have Alzheimer's. Guidelines from organizations like the Alzheimer's Association and the American Academy of Neurology do not currently recommend omega-3 supplementation specifically for AD treatment.
In summary, there is a scientific basis and some research supporting omega-3 fatty acids for brain health, but current evidence does not robustly support the efficacy of Omega Blend supplements in treating or significantly slowing Alzheimer's disease. The evidence is weak to moderate overall, hence the rating of 2 out of 5.
Other ingredients used for Alzheimer's Disease
acai berryacetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
l-carnosine
l-serine
l-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
sulforaphane glucosinolate
tocotrienols
trans-pterostilbene
tributyrin
ubiquinol
Urolithin A
vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
mulberry
β-nicotinamide mononucleotide (NMN)
gastrodia
tinospora cordifolia
lingzhi
morus
ferulic acid
cistanche
ganoderma
royal jelly
terpene lactones
polyphenols
hypothalamus
herbal blend (proprietary)
algae
cocoa
AMP-activated protein kinase (AMPK)
soy isoflavones
2-(carbamimidoyl-methyl-amino) ethoxyphosphonic acid
7,8-Dihydroxyflavone
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Aronia melanocarpa
Anserine
Avocado
Agmatine
Acetylcholine
Amentoflavone
Acacetin
Alpha-Lipoic Acid
Astragaloside
Ampelopsin
Aniracetam
Apocynin
Black Seed
Bilobalide
Butylphthalide
Beta-hydroxybutyrate
Bacopin
Baicalein
Benfotiamine
Basidiomycota
Brahmi
Bacopa
Bifidobacteria
bacoside
Baicalin
Caffeic Acid
Centrophenoxine
Camellia sinensis
Caryophyllene
Cinnamomum
Crocin
Carnosine
Catalpol
Cyanidin
Curcuminoid
Curcumen
Chinese Ligustrum berry
Creatine
Curcuma
C-Phycocyanin
Convolvulus prostratus
Crocetin
Cytidine
Carnosic acid
Cannabigerol
Docosahexaenoic Acid
Decursin
Dihydrolipoic Acid
epicatechin
Ellagic Acid
Ergothioneine
Eicosapentaenoic Acid
Estrogen
Ecklonia
Flavonoids
Flavonones
Ketone Salts
walnut