Evidence supporting the use of: Polysaccharides
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Polysaccharides, particularly those derived from medicinal mushrooms (such as Ganoderma lucidum and Coriolus versicolor), seaweeds, and certain plants, have been investigated for their neuroprotective effects in the context of Alzheimer's Disease (AD). Preclinical studies (in vitro and animal models) suggest that some polysaccharides can exert antioxidant, anti-inflammatory, and anti-amyloidogenic effects, which are relevant to AD pathology. For example, beta-glucans and other polysaccharides may modulate immune responses, reduce oxidative stress, and inhibit the aggregation of beta-amyloid plaques, a hallmark of AD. However, despite these promising mechanisms, robust clinical evidence in humans is lacking. Only a few small-scale or preliminary clinical trials have been conducted, and results are inconclusive or not yet peer-reviewed. There is currently insufficient high-quality, large-scale human data to recommend polysaccharide supplementation as a treatment or preventive strategy for Alzheimer's Disease. Therefore, their use is primarily justified by mechanistic plausibility and preclinical research rather than strong clinical validation.

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astaxanthin
berberine
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beta caryophyllene
bifidobacterium longum
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butyrate triglyceride
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DHA (docosahexaeonic acid)
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epigallocatechin gallate (EGCG)
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flavonols
gamma tocopherol
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glycerophosphocholine (GPC)
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green tea
hemp oil
hesperetin
hesperidin
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l-serine
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lutein
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lycopene
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marine lipid
matcha
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niacinamide (vitamin B3)
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olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
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pomegranate
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Products containing Polysaccharides

We currently have no products on Vitabase that contain this ingredient.