Relationship: Alzheimer's Disease and vitamin C

Evidence supporting the use of: Vitamin C
For the health condition: Alzheimer's Disease

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin C (ascorbic acid) has been studied for its potential role in supporting brain health and possibly slowing the progression of Alzheimer's Disease (AD). The rationale for its use is primarily based on its well-known antioxidant properties. In Alzheimer's Disease, oxidative stress is believed to contribute to neuronal damage and cognitive decline. Vitamin C, being a potent antioxidant, can neutralize free radicals and reduce oxidative stress, which has led to the hypothesis that it might protect against neurodegeneration.

Some observational studies have shown that individuals with higher dietary intake or plasma levels of vitamin C have a lower risk of developing dementia, including AD. However, these studies do not prove causation. Randomized controlled trials (RCTs) evaluating vitamin C supplementation in AD patients are limited and have yielded inconclusive results. Most have not shown significant improvements in cognitive outcomes with vitamin C supplementation alone.

Vitamin C is often included in combination antioxidant regimens (with vitamin E and other micronutrients) in research, making it difficult to isolate its specific effects. Current scientific consensus is that while vitamin C is important for overall neurological health, there is insufficient evidence to recommend high-dose supplementation specifically for the treatment or prevention of Alzheimer's Disease. Thus, the use of vitamin C for this purpose is supported by a plausible scientific rationale and some weak observational data, but robust clinical validation is lacking.

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Acai berry
Acetyl L-carnitine
Akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
Bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
Cannabis sativa oil
caprylic acid
catechins
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaenoic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
L-carnosine
L-serine
L-theanine
Lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
magnesium
Marine lipid
Matcha
medium chain triglycerides (MCT)
Melatonin
N-acetyl-cysteine (NAC)
Naringin
Niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic compounds
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
selenium
sulforaphane glucosinolate
tocotrienols
Trans-pterostilbene
tributyrin
ubiquinol
Urolithin A
Vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
Mulberry
β-nicotinamide mononucleotide (NMN)
gastrodia
Tinospora cordifolia
lingzhi
Morus
ferulic acid
cistanche
ganoderma
royal jelly
terpene lactones
polyphenols
herbal blend (proprietary)
Algae
cocoa
AMP-activated protein kinase (AMPK)
soy isoflavones
2-(carbamimidoyl-methyl-amino) ethoxyphosphonic acid
7,8-Dihydroxyflavone
7,14-Hydroxy-Docosapentaenoic Acid
apigenin
Aronia melanocarpa
anserine
avocado
Agmatine
Acetylcholine
amentoflavone
Acacetin
alpha-lipoic acid
astragaloside
ampelopsin
aniracetam
apocynin
black seed
bilobalide
butylphthalide
beta-hydroxybutyrate
Bacopin
baicalein
benfotiamine
Basidiomycota
brahmi
Bacopa
Bifidobacteria
bacoside
baicalin
caffeic Acid
centrophenoxine
Camellia sinensis
caryophyllene
Cinnamomum
crocin
Carnosine
catalpol
cyanidin
Curcuminoid
curcumen
Chinese Ligustrum berry
creatine
Curcuma
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Convolvulus prostratus
crocetin
cytidine
carnosic acid
cannabigerol
docosahexaenoic Acid
decursin
dihydrolipoic acid
epicatechin
ellagic acid
ergothioneine
eicosapentaenoic acid
estrogen
Ecklonia
flavonoids
fo-ti
fish
fatty acids
fungus
flavanones
flavans
flavonones
flavanols
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gallic acid
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garcinol
ginkgetin
galantamine
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gallate
ginkgolides
ginkgo flavone glycoside
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ginkgoheteroside
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gastrodin
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Hyperoside
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hydroxytyrosol
hericium mushroom
hemp
Homotaurine
iridoids
isoliquiritigenin
isovitexin
icariin
Kaempferol
ketone salts
Lycium
lipids
Maslinic acid
Methylcobalamin
mangiferin
Mulberroside A
Myricitrin
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Monounsaturated fat
malvidin
Marine fat
Methoxylated flavones
magnolol
NADH
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Naringenin
Nigella seed
Nobiletin
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pyrroloquinoline quinone
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polysaccharides
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polyunsaturated fat
punicalagins
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rosmarinic acid
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Turmerones
Tremella
Uncaria
Ursolic Acid
Uridine
Withanolides
Wogonin
Walnut
Xanthohumol
Xanthophyll
Xylaria nigripes

Other health conditions supported by vitamin C

Abrasions
Abscesses
Acne
Acquired Immune Deficiency Syndrome
Addictions (general remedies for)
Addison's Disease
Adrenal Fatigue
Age Spots
Aging (prevention)
Alcoholism
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Anal Fistula or Fissure
Anemia
Antibiotics (alternatives to)
Antibiotics (side effects of)
Anxiety
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Autism
Autoimmune Disorders
Bell's Palsy
Bites and Stings
Bladder Infection
Bleeding (external)
Bleeding (internal)
Blood Poisoning
Boils
Bronchitis
Bruises (healing)
Bruises (prevention)
Burns and Scalds
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Capillary Weakness
Carbuncles
Cardiovascular Disease
Cartilage Damage
Cataracts
Cervical Dysplasia
Chemical Poisoning
Chemotherapy (reducing side effects)
Chicken Pox
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colon (atonic)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (sinus)
Conjunctivitis
Contagious Diseases
Convalescence
Copper Toxicity
Cough (dry)
Cough (general)
Cuts
Cystic Breast Disease
Cystic Fibrosis
Debility
Dementia
Denture Sores
Depression
Diabetes
Diabetic Retinopathy
Environmental Pollution
Epstein Barr Virus
Eye Problems
Eyesight (poor)
Fatigue
Fatty Liver Disease
Free Radical Damage
Gall Stones
Gastritis
Gingivitis
Glaucoma
Gonorrhea
Gout
Hair (loss or thinning)
Hair Care (general)
Heart (weakness)
Heavy Metal Poisoning
Hemorrhoids
Hepatitis
Herpes
Hot Flashes
Hypertension
Infection
Infection (bacterial)
Infection (viral)
Infertility
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Knees (weak)
Laryngitis
Lead Poisoning
Lesions
Leucorrhea
Leukemia
Ligaments (torn or injured)
Liver Detoxification
Lyme Disease
Macular Degeneration
Mastitis
Measles
Memory and Brain Function
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Metabolic Syndrome
Mononucleosis
Mumps
Nose Bleeds
Oral Surgery
Osteoporosis
Pancreatitis
PMS (general)
PMS Type C
PMS Type H
Pneumonia
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Prolapsed Uterus
Prostatitis
Radiation Sickness
Rashes and Hives
Restless Leg Syndrome
Rheumatoid Arthritis
Rhinitis
Rhinitis, Allergic
Rosacea
Scars / Scar Tissue
Schizophrenia
Scratches and Abrasions
Scurvy
Shingles
Shock
Sinus Infection
Skin (infections)
Skin Care (general)
Sore Throat
Spider Veins
Spinal Disks
Sprains
Strep Throat
Stretch Marks
Sunburn
Surgery (healing from)
Surgery (preparation for)
Teeth (loose)
Tendonitis
Thrush
Tickle in Throat
Tonsillitis
Tooth Extraction
Toxemia
Triglycerides (high)
Tuberculosis
Ulcerations (external)
Ulcers
Uric Acid Retention
Urinary Tract Infections
Vaginitis
Varicose Veins
Warts
Wounds and Sores
Wrinkles

Products containing vitamin C

Health Concerns

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Evidence supporting the use of: Vitamin C
For the health condition: Alzheimer's Disease

Table of Contents

Synopsis

Other ingredients used for Alzheimer's Disease

Other health conditions supported by vitamin C

Products containing vitamin C

Health Concerns

Brands

Evidence supporting the use of: Vitamin CFor the health condition: Alzheimer's Disease

Table of Contents

Synopsis

Other ingredients used for Alzheimer's Disease

Other health conditions supported by vitamin C

Products containing vitamin C

Evidence supporting the use of: Vitamin C
For the health condition: Alzheimer's Disease