Evidence supporting the use of: Vitamin D (mixed)
For the health condition: Alzheimer's Disease
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Vitamin D has attracted scientific interest for its potential role in neurodegenerative diseases, including Alzheimer's Disease (AD). Several observational studies have noted that individuals with AD or cognitive decline often have lower serum vitamin D levels compared to healthy controls. Vitamin D receptors are present in the brain, and vitamin D is thought to have neuroprotective effects, including anti-inflammatory and antioxidant properties, which are relevant to AD pathology.
However, while observational evidence suggests an association between vitamin D deficiency and increased risk of cognitive impairment or AD, interventional trials have produced inconsistent results. Some small-scale studies have suggested that vitamin D supplementation may improve cognitive function or slow decline in older adults with low vitamin D levels, but larger and more rigorous randomized controlled trials have not consistently demonstrated a significant benefit in preventing or treating Alzheimer's Disease.
Current consensus in the scientific community is that there is not yet strong evidence to recommend vitamin D supplementation specifically for AD treatment, although correcting deficiency is important for general health. Ongoing research may clarify whether certain subgroups could benefit. Thus, while there is a scientific rationale and some supportive data, the overall level of evidence remains low to moderate.
Other ingredients used for Alzheimer's Disease
acai berryacetyl l-carnitine
akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
amino acids
anthocyanins
ashwagandha
astaxanthin
berberine
berry flavor
beta caryophyllene
bifidobacterium longum
black garlic
black tea
blueberry
broccoli
butyrate triglyceride
caffeine
cannabis sativa oil
caprylic acid
catechins
Chinese salvia root
chokeberry
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
turmeric
curcumin
cyclodextrin
d-alpha tocopherol
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish oil
fish protein
flavonols
gamma tocopherol
genistein
ginkgo biloba
ginseng
glycerophosphocholine (GPC)
grape
green tea
hemp oil
hesperetin
hesperidin
huperzine A
l-carnitine
l-carnosine
l-serine
l-theanine
lentinula edodes mycelia
lion's mane
lutein
luteolin
lycopene
mackerel
magnesium
marine lipid
matcha
medium chain triglycerides (MCT)
melatonin
n-acetyl-cysteine (NAC)
naringin
niacinamide (vitamin B3)
nicotinamide riboside
olive
omega-3 fatty acids
oyster mushroom
phenolic acids
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
polygala root
pomegranate
pregnenolone
butyric acid
pyrroloquinoline disodium salt
quercetin
reishi mushroom
resveratrol
rhizome
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sardines
selenium
sulforaphane glucosinolate
tocotrienols
trans-pterostilbene
tributyrin
ubiquinol
Urolithin A
vinpocetine
vitamin B
vitamin B12
vitamin C
vitamin D
vitamin D3
vitamin E
mulberry
β-nicotinamide mononucleotide (NMN)
gastrodia
tinospora cordifolia
lingzhi
morus
ferulic acid
cistanche
ganoderma
royal jelly
terpene lactones
polyphenols
hypothalamus
herbal blend (proprietary)
algae
cocoa
AMP-activated protein kinase (AMPK)
soy isoflavones
2-(carbamimidoyl-methyl-amino) ethoxyphosphonic acid
7,8-Dihydroxyflavone
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Aronia melanocarpa
Anserine
Avocado
Agmatine
Acetylcholine
Amentoflavone
Acacetin
Alpha-Lipoic Acid
Astragaloside
Ampelopsin
Aniracetam
Apocynin
Black Seed
Bilobalide
Butylphthalide
Beta-hydroxybutyrate
Bacopin
Baicalein
Benfotiamine
Basidiomycota
Brahmi
Bacopa
Bifidobacteria
bacoside
Baicalin
Caffeic Acid
Centrophenoxine
Camellia sinensis
Caryophyllene
Cinnamomum
Crocin
Carnosine
Catalpol
Cyanidin
Curcuminoid
Curcumen
Chinese Ligustrum berry
Creatine
Curcuma
C-Phycocyanin
Convolvulus prostratus
Crocetin
Cytidine
Carnosic acid
Cannabigerol
Docosahexaenoic Acid
Decursin
Dihydrolipoic Acid
epicatechin
Ellagic Acid
Ergothioneine
Eicosapentaenoic Acid
Estrogen
Ecklonia
Flavonoids
Flavonones
Ketone Salts
walnut
Other health conditions supported by Vitamin D (mixed)
Alzheimer's DiseaseAnemia
Arthritis
Asthma
Autoimmune Disorders
Backache
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Chronic Obstructive Pulmonary Disorder
Colds (prevention)
Dementia
Depression
Diabetes
Fatigue
Fibromyalgia Syndrome
Grave's Disease
Hair (loss or thinning)
Hashimoto's Disease
Heart (weakness)
Hypertension
Hypothyroid
Inflammation
Influenza
Lupus
Memory and Brain Function
Menopause
Migraine
Multiple Sclerosis
Osteoporosis
Parkinson's Disease
Psoriasis
Rheumatoid Arthritis
Seasonal Affective Disorder
Tuberculosis
Wounds and Sores