Evidence supporting the use of: Blend (Combination)
For the health condition: Amenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

A blend (combination) of herbs has traditionally been used in various systems of medicine, such as Traditional Chinese Medicine (TCM) and Ayurveda, to support the treatment of amenorrhea (the absence of menstruation). In TCM, combinations like "Ba Zhen Tang" and "Si Wu Tang" are classic formulas prescribed to nourish blood and regulate menstruation. These blends typically include herbs such as Angelica sinensis (Dong Quai), Paeonia lactiflora (White Peony), Rehmannia glutinosa, and Ligusticum chuanxiong, among others. The rationale for combining these herbs is to address multiple potential causes of amenorrhea, such as blood deficiency, hormonal imbalance, and energy (Qi) stagnation. While there is a long tradition of using these herbal combinations, high-quality scientific evidence supporting their efficacy in treating amenorrhea is limited. Some small clinical trials and preclinical studies suggest that certain combinations may influence hormone levels or promote menstrual regularity, but results are inconsistent and often lack rigorous methodology. Thus, the primary justification for their use is based on historical and empirical use rather than robust clinical validation. It should also be noted that the safety and efficacy of these combinations can vary depending on the specific herbs used and individual patient factors. More well-designed clinical trials are needed to substantiate traditional claims.

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