Evidence supporting the use of: Blend (herb/botanical)
For the health condition: Amenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Amenorrhea, the absence of menstruation, has been addressed in traditional herbal medicine systems using various blends of botanicals. Common herbs included in such blends are Vitex agnus-castus (chaste tree berry), Angelica sinensis (dong quai), and Paeonia lactiflora (white peony), among others. The use of herbal blends for amenorrhea is primarily justified by historical and traditional practices, especially in Traditional Chinese Medicine (TCM) and Western herbalism. In these traditions, such herbs are believed to harmonize hormonal cycles, improve blood flow, or address underlying constitutional imbalances thought to contribute to menstrual irregularities. For example, dong quai is often called "female ginseng" and is used in TCM formulas aimed at regulating the menstrual cycle.

However, scientific evidence supporting the effectiveness of multi-herb blends for amenorrhea is limited. Most studies focus on single herbs (such as Vitex) rather than complex mixtures, and clinical trials are generally small, of low quality, or show mixed results. Systematic reviews note a lack of rigorous, high-quality clinical data to conclusively support the use of herbal blends for amenorrhea. Therefore, while traditional use is well-documented and some preclinical evidence may suggest plausible mechanisms, robust scientific validation is lacking. Use of such blends should be approached with caution and ideally under the guidance of a qualified healthcare provider.

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