Chinese Dodder (Cuscuta chinensis), known as Tu Si Zi in Traditional Chinese Medicine (TCM), has been used for centuries to address various reproductive and gynecological disorders, including amenorrhea (the absence of menstruation). Its traditional use is rooted in TCM theory, where it is believed to tonify the Kidney and Liver systems, which are thought to play key roles in regulating the menstrual cycle. In classical TCM texts, Chinese Dodder seeds are included in herbal formulas to "nourish essence" and "tonify yang," both considered important for restoring menstruation and fertility.

Despite its long-standing traditional use, scientific validation specifically for amenorrhea is limited. Some preclinical studies suggest that Cuscuta chinensis may modulate hormone levels or possess phytoestrogenic activity, but these findings are not robustly linked to clinical outcomes in amenorrhea. There are few, if any, high-quality randomized controlled trials investigating its efficacy for this condition in humans. Thus, the evidence supporting its use for amenorrhea primarily comes from historical usage in TCM, expert opinion, and anecdotal reports rather than rigorous scientific research.

In summary, Chinese Dodder is traditionally used for amenorrhea in TCM, but scientific evidence for its effectiveness in this specific context remains weak and inconclusive.