Evidence supporting the use of: Chinese Motherwort
For the health condition: Amenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Chinese Motherwort (Leonurus japonicus) has a long history of use in Traditional Chinese Medicine (TCM) for various gynecological conditions, including amenorrhea (the absence of menstruation). In TCM, Chinese Motherwort is believed to invigorate blood circulation, regulate menstruation, and remove blood stasis—concepts fundamental to traditional approaches to treating menstrual disorders. Historical texts and TCM formularies frequently reference its use for promoting menstrual flow and addressing conditions like amenorrhea, dysmenorrhea, and postpartum abdominal pain.

However, scientific validation for these traditional uses is limited. While a few preclinical studies suggest that Leonurus japonicus may have uterotonic and circulatory effects, high-quality clinical trials supporting its efficacy for amenorrhea specifically are lacking. Most available studies are either in vitro, animal-based, or focused on broader reproductive health rather than amenorrhea alone. There is insufficient robust evidence from randomized controlled trials to fully validate its effectiveness for this indication by modern scientific standards.

In summary, the use of Chinese Motherwort for amenorrhea is primarily justified by traditional usage in Chinese medicine, with some pharmacological rationale but a lack of strong clinical evidence. Its role in TCM persists, but those seeking scientifically validated treatments for amenorrhea should consider evidence-based options alongside, or in place of, traditional herbal remedies.

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