Evidence supporting the use of: False unicorn root
For the health condition: Amenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

False Unicorn Root (Chamaelirium luteum) has a long history of use in North American herbal medicine, particularly among Native American tribes and 19th-century eclectic physicians, for a variety of gynecological issues, including amenorrhea (absence of menstruation). Traditional herbalists believed that False Unicorn Root could “tone” the uterus and help restore menstrual cycles when they were absent or irregular. The root was commonly included in herbal formulas referred to as “female regulators.” However, the evidence supporting its use is almost entirely anecdotal and based on folklore or historical texts rather than modern scientific research.

To date, there are no reliable clinical trials or rigorous scientific studies demonstrating that False Unicorn Root is effective for treating amenorrhea. Most contemporary sources cite its use based on traditional practices rather than empirical data. Reports in herbal compendia, such as the King’s American Dispensatory and various Materia Medica texts from the late 19th and early 20th centuries, note its use for “uterine atony” and “menstrual irregularities” but without supporting clinical evidence. Modern reference works and monographs (e.g., American Herbal Pharmacopoeia) generally acknowledge the lack of scientific validation for these uses.

In summary, while False Unicorn Root has a traditional role in treating amenorrhea, its efficacy for this condition is not supported by modern scientific research, and the evidence is weak and primarily historical.

More about false unicorn root
More about Amenorrhea

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