Evidence supporting the use of: Paeonia moutan
For the health condition: Amenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Paeonia moutan, commonly known as Moutan Cortex or Tree Peony Root Bark, has a long-standing use in Traditional Chinese Medicine (TCM) for gynecological disorders, including amenorrhea (the absence of menstruation). According to TCM theory, Paeonia moutan is used to invigorate the blood, dispel blood stasis, and clear heat, which are believed to be underlying causes of amenorrhea. Classical texts and TCM practitioners often include Paeonia moutan in herbal formulas such as "Xiao Yao San" and "Si Wu Tang," which are prescribed for menstrual irregularities and related symptoms. Scientific studies on Paeonia moutan’s efficacy specifically for amenorrhea are limited, and most available evidence is either preclinical or extrapolated from research on its effects on blood circulation and hormone regulation. Some modern pharmacological studies suggest that compounds in Paeonia species have anti-inflammatory and antispasmodic properties and may influence hormone levels, but these findings are not directly tied to controlled clinical trials for amenorrhea. Thus, its use for this condition remains primarily justified by traditional practice rather than robust scientific validation.

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