Evidence supporting the use of: Pituitary
For the health condition: Amenorrhea
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
The pituitary gland plays a central role in regulating the menstrual cycle by secreting hormones such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which directly influence ovarian function. Dysfunction of the pituitary gland can lead to amenorrhea (the absence of menstruation), particularly in cases of hypopituitarism or pituitary tumors. In clinical practice, treatment of amenorrhea sometimes involves pituitary-derived hormones or synthetic analogues (such as gonadotropins) to stimulate ovulation and restore menstrual cycles, especially when amenorrhea is due to pituitary insufficiency.
Scientific evidence supports the use of pituitary hormones (not the glandular extract itself, but purified or recombinant versions of its key hormones) for this purpose. For example, exogenous administration of FSH and LH is a standard therapy in reproductive endocrinology for ovulation induction in women with hypogonadotropic hypogonadism, a condition characterized by deficient pituitary hormone production leading to amenorrhea. However, the use of whole pituitary extracts (glandular therapy) has largely been replaced by these more precise and safer hormone preparations.
Thus, the support for using pituitary-derived hormones in treating certain types of amenorrhea is scientifically validated, but the direct use of "pituitary" as a supplement or glandular product is not widely supported in modern evidence-based medicine. Most clinical use today focuses on purified or recombinant hormones rather than glandular extracts.
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