Pulsatilla, a plant also known as Pasque flower, has a long-standing history of use in traditional herbal and homeopathic medicine, particularly in Europe. Traditionally, it has been employed to address various menstrual disorders, including amenorrhea (the absence of menstruation), dysmenorrhea (painful menstruation), and other gynecological complaints. Accounts from historical herbal texts and practitioners describe Pulsatilla as a remedy to "stimulate menstrual flow," especially when amenorrhea is thought to be related to emotional distress or hormonal imbalances. Its use is most commonly associated with homeopathic preparations, where highly diluted forms are administered based on symptom profiles matching Pulsatilla's reputed effects.

However, there is a lack of robust scientific evidence to support these traditional claims. Controlled clinical studies evaluating the efficacy of Pulsatilla for amenorrhea are virtually nonexistent. Modern herbal medicine sources often mention it based on tradition or anecdotal reports, rather than scientific validation. As such, the evidence supporting its use for amenorrhea is minimal and rooted primarily in historical and homeopathic practice, not in rigorous clinical research. Anyone considering Pulsatilla for amenorrhea should consult a healthcare professional, as its efficacy and safety for this condition are not established through scientific study.