Evidence supporting the use of: Squaw Vine
For the health condition: Amenorrhea

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Squaw Vine (Mitchella repens) has been traditionally used in North American herbalism, particularly by Indigenous peoples and early American herbalists, to support various aspects of women's reproductive health, including amenorrhea (the absence of menstruation). Historical records indicate its use as a uterine tonic and as part of formulas intended to "prepare" women for childbirth or to regulate menstrual cycles. However, the evidence supporting its efficacy for amenorrhea is largely anecdotal and based on traditional knowledge rather than clinical studies. There is a lack of modern scientific research, such as randomized controlled trials, to validate these traditional claims. No well-established mechanisms of action have been identified, and authoritative herbal references often note the absence of direct scientific evidence for this specific use. Thus, while Squaw Vine's reputation in herbalism is rooted in tradition, the quality and quantity of evidence are quite low, and its effectiveness for amenorrhea remains unproven by current scientific standards.

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