Evidence supporting the use of: Sanguisorba
For the health condition: Anal Fistula or Fissure

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Sanguisorba officinalis (commonly known as great burnet) has been used in traditional Chinese medicine and other herbal traditions primarily for its hemostatic (bleeding-stopping), anti-inflammatory, and wound-healing properties. Its traditional use in the management of anal fistula and anal fissure arises from these attributes, with herbal decoctions or topical preparations believed to promote healing of mucosal tissues, reduce bleeding, and limit inflammation. Several classical Chinese medical texts include Sanguisorba (Di Yu) in formulations for treating hemorrhoids, anal bleeding, and chronic anal wounds, often in combination with other herbs such as Sophora flavescens (Ku Shen) and Coptis chinensis (Huang Lian).

Scientific validation for these uses in the context of anal fistula or fissure is limited. Some pharmacological studies have demonstrated that Sanguisorba contains compounds with anti-inflammatory, antibacterial, and astringent effects, which could theoretically be beneficial in wound healing and infection control. However, robust clinical trials specifically evaluating Sanguisorba for anal fistula or fissure are lacking. As such, while its use is broadly justified by tradition and some supportive pharmacological data, high-quality clinical evidence supporting its efficacy in these specific conditions is not available. Thus, the rating reflects the preponderance of traditional usage with limited direct scientific evidence.

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