Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Manganese sulfate is sometimes included in multivitamin and mineral supplements, and there is a limited scientific rationale for its use in supporting anemia, although the evidence is not robust. Manganese is an essential trace mineral involved in various enzymatic reactions, including those necessary for the metabolism of carbohydrates, amino acids, and cholesterol. It also plays a role in the formation of connective tissue and bone. The primary scientific basis for its connection to anemia is that manganese is a cofactor for the enzyme glycosyltransferase, which is involved in the production of glycoproteins necessary for erythropoiesis (red blood cell production). Additionally, manganese is required for the proper functioning of the antioxidant enzyme superoxide dismutase in mitochondria. However, the direct evidence linking manganese sulfate supplementation to the treatment or prevention of anemia in humans is limited. Most cases of anemia are due to deficiencies in iron, vitamin B12, or folic acid rather than manganese. Animal studies have shown that severe manganese deficiency can lead to impaired growth and reproductive function, and in rare cases, anemia, but such deficiencies are extremely uncommon in humans. Supplementation with manganese sulfate is not routinely recommended for anemia unless a specific manganese deficiency is identified, which is rare. Therefore, while there is a scientific basis for manganese being necessary for erythropoiesis, the clinical evidence supporting manganese sulfate supplementation for anemia is weak (rated 2 out of 5).

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Other ingredients used for Anemia

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anchovies
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astragalus
beet
black cumin
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blackberry
bovine
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brussel sprouts
caterpillar mushroom
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collard
cordyceps
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folate
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lactoferrin
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lentinula edodes mycelia
licorice root
liquid liver fractions
maca
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oyster mushroom
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plantain
plum fruit
pollen
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riboflavin (vitamin B2)
sardines
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spinach
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tomato
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Asteracea
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Allium tuberosum
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Other health conditions supported by Manganese sulfate

Anemia

Products containing Manganese sulfate

We currently have no products on Vitabase that contain this ingredient.