Evidence supporting the use of: Pyridoxine (Vitamin B6)
For the health condition: Anemia
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Pyridoxine (Vitamin B6) has a scientifically validated, though specific, role in the management of anemia, particularly sideroblastic anemia. Sideroblastic anemia is a rare disorder characterized by the body's inability to properly incorporate iron into hemoglobin, leading to the presence of ringed sideroblasts in the bone marrow. One of the causes of this type of anemia is a deficiency of Vitamin B6, which is a vital cofactor for the enzyme ALA synthase in the heme synthesis pathway. In cases where sideroblastic anemia is due to a congenital or acquired deficiency of pyridoxine, supplementation can correct the anemia by restoring heme synthesis.
However, the use of Vitamin B6 in treating other forms of anemia, such as iron-deficiency anemia or anemia of chronic disease, is not well-supported by scientific evidence. Most clinical guidelines restrict B6 supplementation to cases where deficiency is demonstrated or where specific forms of anemia (e.g., pyridoxine-responsive sideroblastic anemia) are present. There is no substantial evidence to support the broad use of Vitamin B6 to treat all types of anemia.
In summary, Vitamin B6 is scientifically validated for use in specific, rare forms of anemia but not as a general treatment for anemia. Its use should be reserved for cases where a deficiency is identified or a specific diagnosis (such as sideroblastic anemia) justifies supplementation.
Other ingredients used for Anemia
Alfalfaamino acids
anchovies
apple
ashwagandha
astragalus
beet
black cumin
sesame
blackberry
bovine
bovine liver
bovine spleen
broccoli
Brussel sprouts
caterpillar mushroom
catjang cowpea
chlorella
coconut milk
collard
cordyceps
dog rose
dong quai root
fish protein
folate
fructooligosaccharides (FOS)
fu ling
ginger
ginseng
gooseberry
greens blend (proprietary)
hibiscus
Indian tinospora
iron
jujube
kale
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
Lactoferrin
lemon
Lentinula edodes mycelia
licorice root
liquid liver fractions
maca
Moringa
Nettle
oat
orange
oyster mushroom
parsley
plantain
plum fruit
pollen
pomegranate
pomelo
protein
pumpkin
pyridoxal-5-phosphate (P-5-P)
quail egg
quinoa
rehmannia glutinosa
reishi mushroom
rhizome
riboflavin (vitamin B2)
shiitake mushroom
soybean
spinach
spirulina
Triphala
vitamin A
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
Watercress
wheat grass
Mulberry
Yeast
Zinc
suma
shen-chu
Mugwort
nut grass
punarnava
Tinospora cordifolia
blackboard tree
Caesalpinia crista
Rubia cordifolia
bee pollen
peony
lingzhi
Morus
root tuber
cistanche
dodder
ganoderma
hyacinth bean
lotus seed
Morinda
Trichosanthes
dulse leaf
royal jelly
trace minerals
purslane
fulvic acid
aster root
shepherd's purse
wheat germ
biota seed
goji berry
paw paw
amaranth
millet seed
herbal blend (proprietary)
Algae
kidney beans
chickpea protein
5-methyltetrahydrofolate glucosamine
animal Tissue
Ardisia
Angelica
Achyranthes
Auricularia
Abrus
Alchornea
Autumn Olive
Ajuga
Aerva lanata
astragaloside
Adzuki bean
Agrimonia pilosa
Asteraceae
Algal protein
Abalone
Allium tuberosum
animal protein
bermuda grass
Bidens pilosa
breadnut
Blepharis
Beef Protein
Butea monosperma
beef
Beef liver
buffalo
bok choy
bone marrow
bovine protein
bael
bean
butternut
berry
black gram
Baccharoides anthelmintica
broad bean
bee products
black nightshade
Bombax
borassus palm
Borassus aethiopum
Blue-Green Alage
banana
baobab
Buckwheat
Boerhavia diffusa
bird\'s nest
cumin
cowpea
Codonopsis
Cynomorium
capillary artemisia
Cyathula
cashew
Citrus
cereal grass
Chlorophytum
chard
Curcuma
C-phycocyanin
canihua
chestnut
cytokines
cassava
Celosia
currant
deer root
dehydroascorbic acid
dragon fruit
dong quai
Dolichos
date
dulse
Eupolyphaga sinensis
empresstree
egg
Eclipta
European five-finger grass
Embelia
fig
folinic acid
folic acid
fruit
ferritin
fo-ti
fish
ferric ammonium citrate
Fagopyrum
Foxtail millet
ferric citrate
ferric orthophosphate
Ginsenosides
garden cress
garbanzo bean
horse gram
Histidine
Hygrophila
Helicteres isora
hijiki
Huang hua
intrinsic factor
Ilex
Indian coraltree
jungli-bean
Kokilaksha
kiwi
Lycium
lucuma
Laver
Legume protein
longan
Lentil
Land Cress
Leptadenia
little ironweed
Loranthus
Labisia pumila
Molasses
Methylcobalamin
Mineral ascorbate
Mung bean
Marine protein
Millet
Momordica
Microcos
Nigella seed
Nori
Onosma bracteatum
Phycocyanin
Phyllanthus
Palmyra
Phaeophyceae
Plankton
Prunus
Phosphate ascorbate
Portulaca
Polygonatum
Persimmon
Physalis angulata
Rubus
Rehmannia
Rubiaceae
Rubia yunnanensis
Rumex acetosa
Rosa roxburghii
Sicklepod
Sesbania
Solanum anguivi
Stellaria dichotoma
Stereospermum
Shilajit
Terminalia
Taxillus chinensis
Tayuya
Thaumatococcus daniellii
Tamarind
Taraxacum
Tropical jewel hisbiscus
Vegetable Protein
Wakame
Wulinshen
Yellow Dock
Zucchini
Other health conditions supported by Pyridoxine (Vitamin B6)
AlcoholismAnemia
Anxiety
Anxiety Disorders
Burning Feet or Hands
Cancer Treatment (reducing side effects)
Canker Sores
Carpal Tunnel Syndrome