Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin B12 (cyanocobalamin) is scientifically validated for the treatment and prevention of certain types of anemia, particularly megaloblastic anemia and pernicious anemia. These conditions are caused by a deficiency of vitamin B12, which is essential for DNA synthesis and normal red blood cell formation in the bone marrow. Without adequate vitamin B12, red blood cells become large, immature, and dysfunctional, resulting in megaloblastic anemia.

The relationship between vitamin B12 deficiency and anemia was elucidated in the early 20th century, particularly through research on pernicious anemia, a previously fatal disease. The discovery that liver (rich in B12) could treat pernicious anemia led to the identification and isolation of vitamin B12. Subsequent studies have shown that oral or intramuscular administration of vitamin B12 reverses the hematological abnormalities and resolves the anemia in deficient individuals.

Vitamin B12 supplementation is not indicated for all types of anemia, but it is the standard of care for anemia caused by B12 deficiency, whether due to dietary insufficiency, malabsorption (e.g., pernicious anemia, gastrointestinal surgery), or inherited disorders of B12 metabolism. Guidelines from major medical organizations support its use in these contexts. The evidence base includes randomized controlled trials, observational studies, and extensive clinical experience.

More about Vitamin B12 (cyanocobalamin)
More about Anemia

Other ingredients used for Anemia

Alfalfa
amino acids
anchovies
apple
ashwagandha
astragalus
beet
black cumin
sesame
blackberry
bovine
bovine liver
bovine spleen
broccoli
Brussel sprouts
caterpillar mushroom
catjang cowpea
chlorella
coconut milk
collard
cordyceps
dog rose
dong quai root
fish protein
folate
fructooligosaccharides (FOS)
fu ling
ginger
ginseng
gooseberry
greens blend (proprietary)
hibiscus
Indian tinospora
iron
jujube
kale
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
Lactoferrin
lemon
Lentinula edodes mycelia
licorice root
liquid liver fractions
maca
Moringa
Nettle
oat
orange
oyster mushroom
parsley
plantain
plum fruit
pollen
pomegranate
pomelo
protein
pumpkin
pyridoxal-5-phosphate (P-5-P)
quail egg
quinoa
rehmannia glutinosa
reishi mushroom
rhizome
riboflavin (vitamin B2)
shiitake mushroom
soybean
spinach
spirulina
Triphala
vitamin A
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
Watercress
wheat grass
Mulberry
Yeast
Zinc
suma
shen-chu
Mugwort
nut grass
punarnava
Tinospora cordifolia
blackboard tree
Caesalpinia crista
Rubia cordifolia
bee pollen
peony
lingzhi
Morus
root tuber
cistanche
dodder
ganoderma
hyacinth bean
lotus seed
Morinda
Trichosanthes
dulse leaf
royal jelly
trace minerals
purslane
fulvic acid
aster root
shepherd's purse
wheat germ
biota seed
goji berry
paw paw
amaranth
millet seed
herbal blend (proprietary)
Algae
kidney beans
chickpea protein
5-methyltetrahydrofolate glucosamine
animal Tissue
Ardisia
Angelica
Achyranthes
Auricularia
Abrus
Alchornea
Autumn Olive
Ajuga
Aerva lanata
astragaloside
Adzuki bean
Agrimonia pilosa
Asteraceae
Algal protein
Abalone
Allium tuberosum
animal protein
bermuda grass
Bidens pilosa
breadnut
Blepharis
Beef Protein
Butea monosperma
beef
Beef liver
buffalo
bok choy
bone marrow
bovine protein
bael
bean
butternut
berry
black gram
Baccharoides anthelmintica
broad bean
bee products
black nightshade
Bombax
borassus palm
Borassus aethiopum
Blue-Green Alage
banana
baobab
Buckwheat
Boerhavia diffusa
bird\'s nest
cumin
cowpea
Codonopsis
Cynomorium
capillary artemisia
Cyathula
cashew
Citrus
cereal grass
Chlorophytum
chard
Curcuma
C-phycocyanin
canihua
chestnut
cytokines
cassava
Celosia
currant
deer root
dehydroascorbic acid
dragon fruit
dong quai
Dolichos
date
dulse
Eupolyphaga sinensis
empresstree
egg
Eclipta
European five-finger grass
Embelia
fig
folinic acid
folic acid
fruit
ferritin
fo-ti
fish
ferric ammonium citrate
Fagopyrum
Foxtail millet
ferric citrate
ferric orthophosphate
Ginsenosides
garden cress
garbanzo bean
horse gram
Histidine
Hygrophila
Helicteres isora
hijiki
Huang hua
intrinsic factor
Ilex
Indian coraltree
jungli-bean
Kokilaksha
kiwi
Lycium
lucuma
Laver
Legume protein
longan
Lentil
Land Cress
Leptadenia
little ironweed
Loranthus
Labisia pumila
Molasses
Methylcobalamin
Mineral ascorbate
Mung bean
Marine protein
Millet
Momordica
Microcos
Nigella seed
Nori
Onosma bracteatum
Phycocyanin
Phyllanthus
Palmyra
Phaeophyceae
Plankton
Prunus
Phosphate ascorbate
Portulaca
Polygonatum
Persimmon
Physalis angulata
Rubus
Rehmannia
Rubiaceae
Rubia yunnanensis
Rumex acetosa
Rosa roxburghii
Sicklepod
Sesbania
Solanum anguivi
Stellaria dichotoma
Stereospermum
Shilajit
Terminalia
Taxillus chinensis
Tayuya
Thaumatococcus daniellii
Tamarind
Taraxacum
Tropical jewel hisbiscus
Vegetable Protein
Wakame
Wulinshen
Yellow Dock
Zucchini

Other health conditions supported by Vitamin B12 (cyanocobalamin)

Anemia
Depression
Fatigue
Memory and Brain Function
Peripheral Neuropathy
Pernicious Anemia
Wasting

Products containing Vitamin B12 (cyanocobalamin)

We currently have no products on Vitabase that contain this ingredient.