Evidence supporting the use of: Vitamin B12 (mixed)
For the health condition: Anemia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin B12 (cobalamin) is scientifically validated for the treatment and prevention of certain types of anemia, particularly megaloblastic anemia and pernicious anemia. Megaloblastic anemia is characterized by the production of abnormally large and immature red blood cells due to impaired DNA synthesis, which results from deficiencies in either vitamin B12 or folate. Pernicious anemia is specifically caused by impaired absorption of vitamin B12, often due to a lack of intrinsic factor in the stomach, and was historically fatal before vitamin B12 therapy became available.

Numerous clinical studies and guidelines support the use of vitamin B12 supplementation—via oral, intramuscular, or subcutaneous routes—for reversing anemia caused by B12 deficiency. Deficiency can result from various causes, such as malabsorption syndromes (e.g., atrophic gastritis, Crohn’s disease), dietary insufficiency (e.g., strict vegan diets), or congenital disorders. Administration of vitamin B12 corrects the underlying deficiency, normalizes red blood cell production, and resolves symptoms of anemia. The use of B12 for this purpose is endorsed by major health organizations, including the World Health Organization (WHO) and the National Institutes of Health (NIH).

In summary, there is robust scientific evidence supporting the use of vitamin B12 for the treatment and prevention of anemia specifically caused by B12 deficiency. Its use in other forms of anemia, such as iron-deficiency anemia, is not supported unless a concurrent B12 deficiency exists.

More about Vitamin B12 (mixed)
More about Anemia

Other ingredients used for Anemia

alfalfa
amino acids
anchovies
apple
ashwagandha
astragalus
beet
black cumin
sesame
blackberry
bovine
bovine liver
bovine spleen
broccoli
brussel sprouts
caterpillar mushroom
catjang cowpea
chlorella
coconut milk
collard
cordyceps
dog rose
dong quai root
fish protein
folate
fructooligosaccharides (FOS)
fu ling
ginger
ginseng
gooseberry
greens blend (proprietary)
hibiscus
Indian tinospora
iron
jujube
kale
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lactoferrin
lemon
lentinula edodes mycelia
licorice root
liquid liver fractions
maca
mackerel
moringa
nettle
oat
orange
oyster mushroom
parsley
plantain
plum fruit
pollen
pomegranate
pomelo
protein
pumpkin
pyridoxal-5-phosphate (P-5-P)
quail egg
quinoa
redcurrant
rehmannia glutinosa
reishi mushroom
rhizome
riboflavin (vitamin B2)
sardines
shiitake mushroom
soybean
spinach
spirulina
tomato
triphala
vitamin A
vitamin B
vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
watercress
wheat grass
mulberry
yeast
zinc
suma
tangerine
shen-chu
mugwort
nut grass
punarnava
tinospora cordifolia
blackboard tree
caesalpinia crista
rubia cordifolia
bee pollen
peony
lingzhi
morus
root tuber
cistanche
dodder
ganoderma
hyacinth bean
lotus seed
morinda
trichosanthes
dulse leaf
royal jelly
trace minerals
purslane
fulvic acid
aster root
shepherd's purse
wheat germ
biota seed
goji berry
paw paw
amaranth
millet seed
herbal blend (proprietary)
algae
kidney beans
chickpea protein
17beta-[{1-Ketoethyl}-androsta-1, 4-diene-3-one,17a-ol]
17a-di methyl-bol
5-methyltetrahydrofolate glucosamine
Animal Tissue
Ardisia
Angelica
Achyranthes
Auricularia
Abrus
Alchornea
Autumn Olive
Ajuga
Aerva lanata
Astragaloside
Adzuki bean
Agrimonia pilosa
Asteracea
Algal protein
Abalone
Allium tuberosum
Animal protein
Bermuda Grass
Bidens pilosa
Breadnut
Blepharis
Beef Protein
Butea monosperma
Beef
Beef liver
Buffalo
Bok Choy
Bone Marrow
Bovine Protein
Bael
Bean
Butternut
berry
Black Gram
Baccharoides anthelmintica
Broad Bean
Bee products
Black Nightshade
Bombax
Borassus Palm
Borassus aethiopum
Blue-Green Alage
banana
Baobab
Buckwheat
Boerhavia diffusa
Bird's nest
Cumin
Cowpea
Codonopsis
Cynomorium
Capillary Artemisia
Cyathula
Cashew
Citrus
Cereal grass
Chlorophytum
Chard
Chicken
Curcuma
C-Phycocyanin
Canihua
Chestnut
Cytokines
Cassava
Celosia
Currant
Duodenum
Deer Root
Dehydroascorbic acid
Dragon Fruit
Dong Quai
Dolichos
Date
Dulse
Eupolyphaga sinensis
Empresstree
Egg
Eclipta
European-Five Finger Grass
Embelia
Fig
Folic Acid
Ferritin
Fish
Ferric Ammonium Citrate
Fagopyrum
Ferric citrate
Ferric orthophosphate
Little ironweed
Molasses
Metal Salt
Zucchini

Products containing Vitamin B12 (mixed)

We currently have no products on Vitabase that contain this ingredient.