Evidence supporting the use of: Vitamin D (cholecalciferol)
For the health condition: Anemia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin D (cholecalciferol) is increasingly recognized for its potential role in supporting or treating certain forms of anemia, but the evidence base is limited and primarily emerging from recent scientific studies rather than traditional use. Traditionally, Vitamin D has not been used to treat anemia. However, contemporary research suggests that Vitamin D may influence erythropoiesis (the production of red blood cells) through several mechanisms, including modulation of inflammation and direct effects on erythroid precursor cells in the bone marrow.

Observational studies have identified an association between low Vitamin D levels and a higher prevalence of anemia, particularly in populations with chronic kidney disease, inflammatory conditions, or in the elderly. Some interventional studies have shown modest improvements in hemoglobin levels or reduced anemia risk after Vitamin D supplementation, especially in patients with concurrent Vitamin D deficiency. The mechanisms proposed include Vitamin D’s ability to suppress inflammatory cytokines (such as IL-6), which can otherwise inhibit erythropoiesis, and its potential effect on erythropoietin sensitivity.

Despite these findings, the overall quality and quantity of evidence are limited. Most studies are small, observational, or have methodological weaknesses. There is insufficient large-scale randomized controlled trial data to firmly establish Vitamin D supplementation as a standard treatment for anemia. Therefore, while there is scientific interest and some preliminary evidence, the support for Vitamin D’s use in anemia is modest and far from definitive.

More about Vitamin D (cholecalciferol)
More about Anemia

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plum fruit
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Products containing Vitamin D (cholecalciferol)

We currently have no products on Vitabase that contain this ingredient.