Evidence supporting the use of: Ligusticum (Unspecified)
For the health condition: Angina

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ligusticum species, particularly Ligusticum chuanxiong (also known as Chuanxiong or Szechuan Lovage), have a long history of use in traditional Chinese medicine (TCM) for promoting blood circulation and alleviating pain, including chest pain that may correspond to angina. In TCM, Chuanxiong is often prescribed as part of herbal formulas to "invigorate the blood" and "dispel wind," and it is frequently used to address cardiovascular symptoms such as chest tightness or pain. However, the attribution of these symptoms to modern biomedical angina (ischemic heart pain) is not always direct, as TCM diagnoses and Western medical diagnoses do not always align.

Regarding scientific validation, the evidence is limited. Some pharmacological studies have identified compounds in Ligusticum (notably ligustilide and ferulic acid) that possess vasodilatory, anti-inflammatory, and anti-platelet properties, which could theoretically be beneficial for angina. However, robust clinical trials in humans specifically evaluating Ligusticum’s efficacy and safety for treating angina are lacking. Most available data come from animal studies or in vitro experiments, and there is insufficient high-quality clinical evidence to support its use in conventional medicine for angina.

In summary, Ligusticum’s use for angina is justified by traditional practices, especially in East Asian herbal medicine, but scientific evidence supporting its effectiveness is weak, meriting a rating of 2 out of 5.

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