Evidence supporting the use of: Trichosanthis
For the health condition: Angina

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Trichosanthis (specifically Trichosanthes kirilowii, known as "Gua Lou" in Traditional Chinese Medicine) has a long history of use in traditional Chinese medicine for treating cardiovascular conditions, including angina pectoris. Traditional texts describe its use for "chest bi syndrome," a term often correlated with symptoms of chest pain, tightness, and discomfort, which are similar to those of angina. Practitioners typically use Trichosanthis fruit or root as part of multi-herb formulations intended to "clear heat," "transform phlegm," and "open the chest."

Scientific studies on Trichosanthis for angina are limited. Some preclinical research suggests Trichosanthis extracts may have vasodilatory, anti-inflammatory, and anticoagulant effects, which could theoretically benefit angina patients by improving coronary blood flow and reducing cardiac workload. However, high-quality clinical trials in humans are lacking. Most available evidence is anecdotal or based on traditional usage rather than rigorous scientific validation.

In summary, the main justification for the use of Trichosanthis in angina is rooted in traditional medicine practices rather than strong scientific evidence. While there are plausible mechanisms based on laboratory research, the overall evidence supporting its efficacy for angina in humans is weak and insufficient for formal medical recommendations.

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