Evidence supporting the use of: Vitamin B1
For the health condition: Anorexia

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B1 (thiamine) is scientifically used to support the treatment of anorexia, primarily due to the risk of thiamine deficiency in individuals with significantly reduced nutritional intake. Anorexia nervosa, a psychiatric disorder characterized by self-induced starvation and extreme weight loss, is associated with malnutrition and various micronutrient deficiencies, including thiamine. Thiamine is an essential coenzyme in carbohydrate metabolism and neural function; deficiency can lead to severe neurological complications such as Wernicke's encephalopathy, which can be life-threatening if untreated. Clinical guidelines, such as those from the National Institute for Health and Care Excellence (NICE) and other expert consensus statements, recommend thiamine supplementation as part of the medical management of patients with malnutrition or at risk of refeeding syndrome, including those with anorexia nervosa. The evidence supporting routine thiamine supplementation in this context is based on observational data, expert opinion, and case series documenting the prevention of neurological complications. However, there are limited randomized controlled trials specifically evaluating thiamine supplementation in anorexia nervosa, so the evidence strength is moderate (rated as 3). The primary goal is to prevent deficiency and its complications during nutritional rehabilitation rather than to treat anorexia itself.

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Products containing Vitamin B1

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