Evidence supporting the use of: Alantolactone
For the health condition: Antibiotics (alternatives to)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alantolactone is a naturally occurring sesquiterpene lactone found in the roots of Inula helenium (elecampane) and has been traditionally used in herbal medicine for respiratory and digestive ailments. In recent years, a growing body of preclinical research has investigated alantolactone’s antimicrobial properties.

Scientific evidence: Laboratory (in vitro) studies have shown that alantolactone exhibits antibacterial activity against several Gram-positive and Gram-negative bacteria, including Staphylococcus aureus and Escherichia coli. It is believed to disrupt bacterial cell membranes and inhibit biofilm formation. Some studies have also demonstrated potential synergistic effects when alantolactone is combined with conventional antibiotics, possibly enhancing their efficacy against resistant strains.

However, the current evidence is limited to cell culture and animal studies; there are no clinical trials in humans that confirm its efficacy or safety as an antibiotic alternative or adjunct. Thus, while there is a scientific rationale and promising preliminary data, these findings have not yet translated into clinical recommendations or widespread therapeutic use.

Conclusion: Alantolactone has demonstrated antimicrobial activity in preclinical studies, justifying ongoing research interest. However, the overall strength of evidence is low (rated 2 out of 5) due to the absence of human clinical trials and established dosing or safety profiles.

More about Alantolactone
More about Antibiotics (alternatives to)

Other ingredients used for Antibiotics (alternatives to)

2'-Fucosyllactose
Ajoene
astragalus
bacillus clausii
bacillus subtilis
berberine
black cumin
black walnut
caprylic acid
caterpillar mushroom
clove
colostrum
Coptis chinensis
turmeric
curcumin
epigallocatechin gallate (EGCG)
garlic bulb
ginger
goldenseal
gooseberry
green tea
horseradish
Indian tinospora
honeysuckle
Lactobacillus bulgaricus
Lactobacillus fermentum
Lactobacillus paracasei
lactiplantibacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus salivarius
Lactococcus lactis
Lactoferrin
Lactoperoxidase
lauric acid
Lentinula edodes mycelia
Mastic gum
Monolaurin
oregano
oregon grape
oyster mushroom
phenolic compounds
plantain
butyric acid
rhizome
sage
shiitake mushroom
thyme
vitamin C
Wasabi
Zinc
Yellow root
papaya
Neem tree
Clerodendrum indicum
pistacia integerrima gall
paederia foetida
pau d'arco
Myrrh
Morinda
oriental arborvitae
melaleuca alternifolia
Algae
geranium
red root
10-Hydroxy-2-Decanoic Acid
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
3-Phenyllactic Acid
alpha-terpineol
azelaic acid
Allicin
anamu
Alchornea
aucubin
andrographolide
Andrographis
Alstonia scholaris
Asteraceae
Allyl sulfide
Acemannan
Algal protein
Alliin
Alantolactone
bee propolis
Bacillus indicus
Baphicacanthus cusia
Bidens pilosa
betulinic acid
Butea monosperma
Brazilian peppertree
bee hive
Basidiomycota
Bacillus licheniformis
Brevibacillus laterosporus
bee products
Bombax
Borassus aethiopum
bacteria
Blue-Green Alage
Bacillus
benzyl isothiocyanate
baicalin
coconut
capric acid
Calotropis gigantea
coconut oil
carvacrol
Chinese raisintree
cinnamic acid
citral
Centipeda
chalcone
Clostridium butyricum
cinnamaldehyde
copaiba oil
Dichrostachys glomerata
European Elder
Embelia
eugenol
flavonoids
Fomes fomentarius
fungus
gallic acid
glyceryl monolaurate
Guava
garlic
golden shower tree
honey
heal-all
Houttuynia
Helicteres isora
Herb Robert
isoquinoline alkaloids
Isatis
Indian coraltree
Indian fagonia
Kefir
Lactobacillus plantarum
Litsea
lichen
lysozyme
Lactobacillus johnsonii
Lantana camara
Leptospermum scoparium
Lactobacillus
L. lactis
Lysimachia
Lauric arginate
Mushroom
Naphthoquinones
Nisin
Nigella seed
Nasturtium
Nimbidin
Oroxylum indicum
Oleuropein
Osha
Oligosaccharides
Onosma bracteatum
Phycocyanin
Propolis
Premna
polysaccharides
pagoda tree
polylysine
Paenibacillus polymyxa
Pentacyclic triterpenoids
phlorotannins
Platycodon
Paris polyphylla
Pleurotus eryngii
Physalis angulata
Petiveria
Plectranthus amboinicus
red alder
Rhus coriaria
Spilanthes
Sicklepod
Sophora
Sesbania
Spanish Needle
Streptomyces
Streptomyces cellulosae
Self-Heal
Sweet Annie
Solanum indicum
Streptomyces fradiae
Sarcandra glabra
Saccharomyces cerevisiae
Streptomyces griseoflavus
saponins
Simaruba
Sulfated polysaccharide
Terminalia
Thymoquinone
Tannins
Tamaricaceae
Thymol
Thaumatococcus daniellii
Tulbaghia
Trametes
Tagetes
Thiosulfinate
Tremella
Wrightia tinctoria
Xanthorrhizol

Products containing Alantolactone

We currently have no products on Vitabase that contain this ingredient.