Evidence supporting the use of: Allicin
For the health condition: Antibiotics (alternatives to)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Allicin, a sulfur-containing compound derived from garlic (Allium sativum), has been studied for its antimicrobial properties. Scientific research has demonstrated that allicin exhibits in vitro antibacterial activity against a range of bacteria, including some antibiotic-resistant strains such as MRSA (methicillin-resistant Staphylococcus aureus) and Escherichia coli. The proposed mechanism involves allicin reacting with thiol groups in bacterial enzymes, disrupting cell function and leading to bacterial death. However, while laboratory studies and some animal research provide evidence for allicin’s antimicrobial effects, robust clinical trials in humans are lacking. The stability and bioavailability of allicin in the human body are also issues, as it is rapidly degraded, which may limit its efficacy as a systemic antibiotic alternative. To date, allicin has not been approved as a substitute for antibiotics in clinical settings, and current medical guidelines do not recommend it for treating bacterial infections. Its use is sometimes promoted in complementary and alternative medicine, but evidence for its effectiveness in humans remains preliminary. Therefore, while there is a scientific basis for allicin’s antibacterial properties, its clinical utility as an antibiotic alternative is not well established.

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Products containing Allicin

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