Evidence supporting the use of: EGCG
For the health condition: Antibiotics (alternatives to)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Epigallocatechin gallate (EGCG), a major catechin found in green tea, has been researched for its antimicrobial properties and its potential role as an adjunct or alternative to antibiotics. Several in vitro studies demonstrate that EGCG can inhibit the growth of a range of bacteria, including antibiotic-resistant strains such as Staphylococcus aureus (including MRSA), Escherichia coli, and Pseudomonas aeruginosa. EGCG appears to disrupt bacterial cell membranes, inhibit enzyme activity, and interfere with the formation of biofilms, which are protective layers that make bacteria more resistant to antibiotics.

Moreover, EGCG has been shown in some preclinical research to synergize with certain antibiotics, enhancing their effectiveness and reducing the required dosage. For example, studies published in journals such as Frontiers in Microbiology (2019) and International Journal of Antimicrobial Agents (2017) report that EGCG can restore the activity of β-lactam antibiotics against resistant bacteria in laboratory settings. However, there is a lack of robust clinical trials in humans, and its bioavailability after oral consumption is limited.

In summary, while there is promising laboratory evidence for EGCG supporting or enhancing antibiotic therapy, especially against resistant bacteria, clinical validation is incomplete. Thus, its use in this context is based on scientific research at the preclinical level, but not yet supported by strong clinical evidence, meriting a moderate evidence rating.

More about EGCG
More about Antibiotics (alternatives to)

Other ingredients used for Antibiotics (alternatives to)

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berberine
black cumin
black walnut
caprylic acid
caterpillar mushroom
clove
colostrum
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turmeric
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epigallocatechin gallate (EGCG)
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green tea
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Products containing EGCG

We currently have no products on Vitabase that contain this ingredient.