Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Oldenlandia, particularly Oldenlandia diffusa (also known as Hedyotis diffusa or "Bai Hua She She Cao" in traditional Chinese medicine), has a long history of use in Asian herbal medicine. It is traditionally used to treat infections, fevers, and inflammatory conditions, functioning as a general "heat-clearing" and detoxifying agent. These traditional uses extend to contexts where antibiotics might be used in Western medicine, such as for bacterial infections or abscesses. While in vitro studies have reported some antibacterial activity of Oldenlandia extracts against certain bacterial strains, these findings are preliminary and have not translated into robust clinical evidence. There are no large-scale randomized controlled trials demonstrating that Oldenlandia can replace antibiotics or effectively treat bacterial infections in humans. Most of the available evidence comes from laboratory or animal studies, and the mechanisms of action remain uncertain. Therefore, while Oldenlandia is traditionally used in place of or alongside antibiotics in some herbal medical systems, its efficacy and safety as an antibiotic alternative are not well substantiated by scientific research. Its use remains primarily based on traditional practices rather than rigorous scientific validation.

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