Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Saccharomyces, particularly Saccharomyces boulardii, has scientific evidence supporting its use as an adjunct to antibiotics, primarily to reduce antibiotic-associated diarrhea (AAD) and the risk of Clostridioides difficile infection. Numerous randomized controlled trials and meta-analyses have demonstrated that supplementation with S. boulardii can significantly decrease the incidence and duration of diarrhea in patients receiving antibiotics. The proposed mechanisms include restoration of gut microbiota balance, enhancement of intestinal barrier function, and modulation of host immune responses.

A 2015 Cochrane review (Goldenberg et al.) analyzing over 30 studies concluded that probiotics, with S. boulardii being one of the most studied, are effective in preventing AAD in both adults and children. Another meta-analysis published in The Lancet Infectious Diseases (2017) supported these findings, highlighting a reduced risk of C. difficile-associated diarrhea in patients using S. boulardii alongside antibiotics.

It is important to note that Saccharomyces is not an "alternative" to antibiotics for treating infections, but is instead used to support gut health during antibiotic therapy. Its use is justified by robust clinical evidence, although it is not a substitute for antibiotics in treating bacterial infections themselves.

More about Saccharomyces
More about Antibiotics (alternatives to)

Other ingredients used for Antibiotics (alternatives to)

Other health conditions supported by Saccharomyces

Products containing Saccharomyces