Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Sodium caprylate is a sodium salt of caprylic acid, a medium-chain fatty acid. There is some scientific evidence that caprylic acid and its salts, including sodium caprylate, possess antimicrobial properties, particularly antifungal effects. In vitro studies have demonstrated that caprylic acid can disrupt the cell membranes of certain fungi (e.g., Candida species) and some bacteria, leading to cell death. This mechanism has led to its inclusion in some dietary supplements and formulations as a means of supporting the body’s defense against fungal and, to a lesser extent, bacterial overgrowth.

However, the evidence for sodium caprylate as a direct alternative or adjunct to antibiotics in treating bacterial infections is limited and mostly preclinical. While laboratory research shows some antibacterial activity, there is a lack of robust clinical trials in humans confirming its efficacy or safety as a substitute for conventional antibiotics. Most clinical applications focus on its antifungal properties, particularly in the context of gut health or as part of protocols aiming to address Candida overgrowth.

In summary, sodium caprylate has some scientific basis for antimicrobial action, mainly antifungal, but evidence supporting its use as an antibiotic alternative is weak, and proper clinical validation is lacking. It should not be considered a replacement for medically necessary antibiotics.

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