Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Solanum indicum, also known as Indian nightshade, has been used traditionally in various systems of medicine, such as Ayurveda and Siddha, primarily for its antimicrobial and anti-inflammatory properties. Historical texts and ethnobotanical surveys document its application in treating infections, respiratory ailments, and other inflammatory conditions. The use of Solanum indicum as an alternative to antibiotics is grounded in its traditional role in managing diseases thought to be caused by microbial agents, long before the advent of modern antibiotics.

Some preliminary in vitro studies have demonstrated that extracts of Solanum indicum possess antibacterial activity against certain Gram-positive and Gram-negative bacteria. Phytochemical constituents such as alkaloids, flavonoids, and glycosides are believed to contribute to these effects. However, these studies are mostly preclinical, with very limited data from animal studies and virtually no clinical trials in humans. As such, while the traditional use as a natural remedy for infections is well documented, robust scientific validation is lacking. There is currently insufficient evidence to recommend Solanum indicum as a reliable alternative to antibiotics in clinical practice, though its traditional use as a supportive remedy persists in some cultures.

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