Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Thaumatococcus daniellii, commonly known for its sweetening agent thaumatin, has been studied for its potential antimicrobial properties. Several scientific studies have investigated extracts from various parts of the plant (particularly leaves and seeds) and found in vitro activity against a range of bacterial strains, including some that are clinically relevant. For example, methanolic and aqueous extracts have demonstrated inhibitory effects on bacteria such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. The proposed mechanisms include disruption of bacterial cell walls and interference with microbial metabolism, attributed to the presence of bioactive compounds such as flavonoids, tannins, and saponins.

However, the evidence is limited to laboratory studies, and there are no robust clinical trials or in vivo studies in humans confirming these effects or establishing safety and efficacy as an antibiotic alternative. While the findings are promising and justify further research, the current evidence is preliminary. The use of Thaumatococcus daniellii as an alternative to conventional antibiotics is not established in clinical practice. Thus, it is scientifically explored, but not yet validated for this purpose in humans.

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