Evidence supporting the use of: Bifidobacterium animalis lactis
For the health condition: Antibiotics (side effects of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bifidobacterium animalis lactis is a probiotic strain that has been studied for its potential to mitigate side effects associated with antibiotic use, particularly antibiotic-associated diarrhea (AAD). Scientific evidence supports its use, though the strength of evidence is considered moderate (rated 3/5) due to variability in study design and outcomes.

Antibiotics can disrupt the normal gut microbiota, leading to gastrointestinal side effects like diarrhea, bloating, and discomfort. Several randomized controlled trials (RCTs) and meta-analyses have investigated the efficacy of probiotics, including Bifidobacterium animalis lactis, in reducing the incidence and severity of AAD. A 2015 meta-analysis published in the Journal of Pediatric Gastroenterology and Nutrition found that certain Bifidobacterium-containing probiotics decreased the risk of AAD in children. Other studies in adults have shown that B. animalis lactis may help restore gut microbial balance during and after antibiotic therapy, thereby reducing gastrointestinal symptoms.

However, not all studies have found significant benefits, and the magnitude of effect can depend on factors such as probiotic dose, duration, and the specific antibiotic used. Overall, while the evidence is supportive and growing, it is not yet conclusive for all patient populations and scenarios. Regulatory bodies recognize probiotics as generally safe, but recommendations for their use alongside antibiotics are not universal. Continued research is warranted to clarify optimal strains, dosing, and patient selection.

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