Evidence supporting the use of: Lactobacillus kefiranofaciens
For the health condition: Antibiotics (side effects of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus kefiranofaciens is a probiotic bacterium commonly found in kefir grains and kefir fermented milk. There is moderate scientific evidence suggesting that this probiotic may help mitigate some side effects associated with antibiotic use, particularly antibiotic-associated diarrhea (AAD). Several animal studies and a small number of human clinical trials have shown that kefir, which contains L. kefiranofaciens among other strains, can help restore gut microbiota balance disrupted by antibiotics. These studies suggest that L. kefiranofaciens may inhibit the growth of pathogenic bacteria, enhance mucosal barrier function, and promote the re-colonization of healthy gut flora after antibiotic therapy. While most clinical research has focused on kefir as a whole rather than isolated L. kefiranofaciens, in vitro studies have demonstrated that this species produces exopolysaccharides (like kefiran) that exhibit protective effects on gut epithelial cells and support beneficial microbial populations.

However, it is important to note that the strength of evidence is limited by the small number of high-quality, strain-specific human studies. Most of the available research is preclinical or involves mixed probiotic preparations. Thus, while there is scientific rationale and some supportive data for the use of L. kefiranofaciens in reducing certain antibiotic side effects, more targeted clinical trials are needed to confirm its efficacy and optimal use in this context.

More about Lactobacillus kefiranofaciens
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Products containing Lactobacillus kefiranofaciens

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