Evidence supporting the use of: Lactobacillus plantarum
For the health condition: Antibiotics (side effects of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus plantarum is a probiotic bacterium commonly used to help mitigate the side effects of antibiotics, such as antibiotic-associated diarrhea (AAD). Scientific studies have shown that antibiotics can disrupt the natural balance of gut microbiota, leading to gastrointestinal symptoms. Probiotics like L. plantarum are thought to restore this balance by replenishing beneficial bacteria. Several randomized controlled trials and meta-analyses have evaluated the efficacy of probiotics, including L. plantarum, in reducing the incidence and severity of AAD. For example, a 2020 review in Frontiers in Microbiology highlighted that L. plantarum supplementation could decrease gastrointestinal symptoms during and after antibiotic therapy, although results can vary depending on the strain and study design. While the evidence is generally supportive, it is not as robust or consistent as for other strains such as L. rhamnosus GG or S. boulardii, leading to a moderate evidence rating. Overall, there is a scientific basis for using L. plantarum to support gut health during antibiotic use, but more large-scale, high-quality studies are needed to confirm its specific efficacy and optimal dosing.

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