Evidence supporting the use of: Lactobacillus reuteri
For the health condition: Antibiotics (side effects of)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Lactobacillus reuteri is a probiotic bacterium that has been studied for its potential to support gut health, particularly during or after antibiotic treatment. Antibiotics often disrupt the balance of normal gut microbiota, leading to side effects such as antibiotic-associated diarrhea (AAD) and increased susceptibility to gastrointestinal infections. Several clinical studies have investigated the use of L. reuteri to mitigate these side effects. For example, randomized controlled trials have shown that supplementation with L. reuteri can reduce the incidence and duration of AAD in both children and adults. A 2012 systematic review and meta-analysis published in "PLOS ONE" found that L. reuteri was effective in preventing AAD in pediatric populations. The proposed mechanisms include restoration of microbial balance, production of antimicrobial substances (such as reuterin), and modulation of immune responses within the gut.

However, while the evidence is promising, it is not as robust or consistent as that for some other probiotic strains (such as Lactobacillus rhamnosus GG or Saccharomyces boulardii). Results can vary depending on the specific population studied, the dosage used, and the outcome measured. Thus, the evidence base is moderate, justifying a rating of 3 out of 5. Overall, L. reuteri is supported by scientific research for helping reduce some antibiotic side effects, but further high-quality studies are needed to strengthen the recommendations for routine use in all patient groups.

More about lactobacillus reuteri
More about Antibiotics (side effects of)