Evidence supporting the use of: Probiotic (unspecified)
For the health condition: Antibiotics (side effects of)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Probiotics are supported by scientific evidence for use in reducing the side effects of antibiotics, particularly antibiotic-associated diarrhea (AAD). Numerous randomized controlled trials and meta-analyses have demonstrated that certain strains of probiotics, including species of Lactobacillus and Saccharomyces boulardii, can significantly reduce the risk and duration of diarrhea in individuals taking antibiotics. Antibiotic therapy often disrupts the balance of gut microbiota, which can lead to gastrointestinal symptoms such as diarrhea, bloating, and cramping. Probiotics help to restore the microbial balance by replenishing beneficial bacteria and inhibiting the growth of pathogenic organisms.

Clinical guidelines from reputable health organizations, including the World Gastroenterology Organisation and the American Gastroenterological Association, acknowledge the role of specific probiotic strains in preventing or mitigating antibiotic-associated side effects. However, the efficacy is strain-specific, and not all probiotic formulations are equally effective. The strongest evidence supports the use of S. boulardii and L. rhamnosus GG for this purpose. Overall, while more research is needed to determine optimal strains, doses, and treatment durations, the use of certain probiotics to counteract antibiotic side effects is validated by a substantial body of clinical evidence.

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