Evidence supporting the use of: Baicalin
For the health condition: Anxiety

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Baicalin is a flavonoid compound derived from the roots of Scutellaria baicalensis, also known as Chinese skullcap. Its use for anxiety stems primarily from traditional Chinese medicine (TCM), where the herb has been utilized for centuries to calm the mind and address symptoms consistent with anxiety and agitation. While baicalin and related compounds are a common ingredient in TCM formulas aimed at “clearing heat” and calming the spirit, modern scientific evidence supporting its efficacy for anxiety in humans is limited and primarily preclinical.

Animal studies have demonstrated that baicalin may exert anxiolytic-like effects, possibly through modulation of GABAergic neurotransmission and anti-inflammatory pathways. For example, some rodent studies have shown reduced anxiety-like behaviors following baicalin administration. However, these findings have not been robustly translated into clinical trials involving humans. To date, there are very few, if any, high-quality randomized controlled trials assessing baicalin's effects on anxiety in people.

In summary, baicalin’s use for anxiety is justified mainly by traditional practice, with supporting animal data but insufficient clinical evidence for strong scientific validation. Its rating reflects promising but preliminary evidence, meriting further research.

More about Baicalin
More about Anxiety

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benegut perilla (proprietary)
bergamot
beta caryophyllene
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bifidobacterium lactis
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cordyceps
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epigallocatechin gallate (EGCG)
fennel
gardenia
ginkgo biloba
ginseng
gotu kola
greek mountain tea
green tea
guayusa
hemp oil
hops
Indian tinospora
inositol
jujube
kava
kudzu
L-glycine
L-theanine
L-tryptophan
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lactobacillus brevis
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
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lavender
lion's mane
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maca
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magnolia
matcha
melatonin
mint
motherwort
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n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
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phosphatidylserine
phytocannabinoids
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prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
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rhizome
rhodiola
rose oil
rosemary
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SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
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spearmint leaf
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Products containing Baicalin

We currently have no products on Vitabase that contain this ingredient.