Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Curcumin, the main active compound in turmeric (Curcuma longa), has garnered interest for its potential anxiolytic (anxiety-reducing) effects. Scientific studies suggest that curcumin may influence neurotransmitter balance, neuroinflammation, and oxidative stress, all of which are implicated in the pathophysiology of anxiety disorders. Preclinical studies in animal models have shown that curcumin supplementation can reduce anxiety-like behaviors, possibly by modulating serotonin and dopamine pathways and reducing inflammation in the brain.

Some small-scale human clinical trials have also explored curcumin's effects on mood. A few randomized controlled trials have reported modest improvements in anxiety symptoms among individuals taking curcumin supplements, particularly in populations with comorbid depression or chronic health conditions. However, these studies are generally limited by small sample sizes, short durations, and methodological shortcomings. Meta-analyses and systematic reviews acknowledge a possible benefit but emphasize the need for larger, high-quality trials before curcumin can be widely recommended for anxiety.

In summary, while there is emerging scientific evidence suggesting curcumin may have anxiolytic properties, the current body of evidence is preliminary and not robust. The evidence rating is therefore 2 out of 5, indicating weak but suggestive scientific support, rather than strong or conclusive evidence. More rigorous clinical research is needed to firmly establish curcumin’s efficacy and optimal dosing for the treatment of anxiety.

More about curcumin
More about Anxiety

Other ingredients used for Anxiety

Other health conditions supported by curcumin

Products containing curcumin

Designs For Health C3 Curcumin Complex
Integrative Therapeutics Curalieve
Thorne Curcumin Phytosome 1000 mg Meriva 500-SF
Thorne Curcumin Phytosome 1000 mg Meriva 500-SF
Thorne Curcumin Phytosome 1000 mg Meriva 500-SF NSF
Thorne Curcumin Phytosome 500 mg SR Meriva-SF
Douglas Laboratories DIM ® Enhanced
Douglas Laboratories DIM ® Enhanced
Thorne EnteroMend NSF
Thorne Joint Support Nutrients AR-Encap
Thorne MediClear Plus
Thorne Metabolic Health
Douglas Laboratories Methlyated Resveratrol Plus
Designs For Health Mitochondrial NRG™
Thorne Multi-Vitamin Elite NSF
Thorne Multi-Vitamin Elite NSF
Thorne PolyResveratrol-SR
Pure Encapsulations ResCu-SR®
Thorne S.A.T.
Designs For Health Senolytic Synergy
Designs For Health Ultimate Antiox Full Spectrum