Evidence supporting the use of: Hemp
For the health condition: Anxiety

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Hemp, specifically its derivative cannabidiol (CBD), has gained attention for its potential anxiolytic (anxiety-reducing) effects. Several studies have explored CBD, a non-psychoactive component of hemp, in the management of anxiety. Clinical trials and preclinical studies suggest that CBD may exert its effects by interacting with the body's endocannabinoid system, particularly the CB1 and CB2 receptors, as well as serotonin receptors (5-HT1A). For instance, a 2011 study published in Neuropsychopharmacology found that CBD reduced anxiety in subjects with social anxiety disorder during a simulated public speaking test. Other small-scale studies and case reports also indicate possible benefits for generalized anxiety disorder, PTSD, and social anxiety, though results are mixed and often limited by small sample sizes and short durations.

It is important to highlight that while the evidence is promising, it is not yet robust. Most studies are preliminary, lack large randomized controlled trials, and often use varying doses and formulations of CBD. Furthermore, whole hemp extract contains many compounds, and the majority of research focuses on isolated CBD rather than the full spectrum of hemp products. Regulatory status and quality of commercial hemp/CBD products also vary widely, affecting consistency and reliability.

In summary, while there is emerging scientific support for the use of hemp-derived CBD in anxiety, the overall quality and quantity of evidence place it at a moderate level (3/5). More rigorous research is needed to confirm efficacy, determine optimal dosing, and ensure safety.

More about Hemp
More about Anxiety

Other ingredients used for Anxiety

5-Hydroxytryptophan (5-HTP)
alpha-pinene
amino acids
ashwagandha
waterhyssop
basil
benegut perilla (proprietary)
bergamot
beta caryophyllene
bifidobacterium bifidum
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
black cumin
bupleurum falcatum
California poppy
cannabis sativa oil
chamomile
Chinese salvia root
citrus oil
clove
cordyceps
curcumin
damiana
DHA (docosahexaeonic acid)
epigallocatechin gallate (EGCG)
fennel
gardenia
ginkgo biloba
ginseng
gotu kola
greek mountain tea
green tea
guayusa
hemp oil
hops
Indian tinospora
inositol
jujube
kava
kudzu
L-glycine
L-theanine
L-tryptophan
lactium casein decapeptide
lactobacillus brevis
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lavender
lion's mane
lithium orotate
maca
magnesium
magnolia
matcha
melatonin
mint
motherwort
muira puama
n-acetyl-cysteine (NAC)
omega-3 fatty acids
passionflower
phellodendron amurense
phosphatidylserine
phytocannabinoids
polygala root
prebiotic blend (proprietary)
pregnenolone
pyridoxal-5-phosphate (P-5-P)
reishi mushroom
relora® (proprietary)
rhizome
rhodiola
rose oil
rosemary
saffron
sage
SAMe (s-adenosyl-l-methionine disulfate p-toluensulfate)
sceletium
skullcap
spearmint leaf
sphaeranthus indicus
thyme
valerian root
velvet bean
vitamin B
vitamin B12
vitamin B6
vitamin C
zinc
squawvine
catnip
gastrodia
cardamom
shen-chu
mugwort
anise
tinospora cordifolia
blackboard tree
peony
lingzhi
lemongrass
kanna
silk tree
chrysanthemum
ganoderma
sweet flag
oriental arborvitae
menthol oil
St. John's Wort
wood betony
hypothalamus
herbal blend (proprietary)
indigo leaves
cocoa
soursop
geranium
star of Bethlehem
7,8-Dihydroxyflavone
Ash
Agastache
Alpha-terpineol
Ardisia
Agrimony
Apigenin
Anamu
Albizia
Aconite
Agmatine
Agarwood
Anemone
Alpha lactalbumin
Asteracea
Aniracetam
Amor seco
Betony
Black Seed
Bifidobacterium
Baikal Skullcap
Bifidobacterium adolescentis
Balsam
Bayleaf
Bacopin
Baicalein
Brahmi
Bacopa
Bee products
Bombax
Bacteria
Bifidobacteria
Bupleurum
bacoside
Baicalin
Borneol
Camellia sinensis
Centella triterpenes
Caryophyllene
Monkey Flower
Cinnamomum
Clary sage
Capillary Artemisia
Citron
Chinese Raisintree
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Capitate Valerian
Curcuma
Catuaba
Cowslip
Cannabidiol
Calamus
Clostridium butyricum
Convolvulus prostratus
Convolvulus Pluricaulis
Clerodendrum indicum
Canscora
Cannabigerol
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
Dragonhead
Erythrina
Essential Oil Blend
Eugenol
Fragrant Rosewood
Ficus religiosa
Fatty acids
Fungus
Gelsemium
Ginsenosides
Griffonia simplicifolia
Glycine
Gardenia jasminoides
Gastrodin
Honokiol
Hyperoside
Heal-All
Hypericum
hyperforin
Herb Robert
Hericium mushroom
Hemp
Honeybush
iridoids
isoliquiritigenin
Ilex
Indian Fagonia
jasmine
Jujubosides
Jatamansi
Kavalactones
Kefir
lemon balm
Lactobacillus plantarum
Lactucarium
Litsea
Linden
Lactococcus rhamnosus
Lactucopicrin
Ligustilides
Limonene
Longan
Lavandin
Lotus
Lycopodium
Lactobacillus johnsonii
Large-Leaved Linden
Lupulinum
Linalool
Mentha haplocalyx
Myrcene
Marjoram
Mimulus
Monoterpenes
Mimosa
Magnolol
Mulungu
Mesembrine
Nardostachys
Nigella Seed
Nymphaea caerulea
Nymphaea nouchali
Nutmeg
Oroxylum indicum
Oolong Tea
Osmanthus
Oxindole alkaloids
Puerain
Phellodendron
Phenylpropanoids
Pulsatilla
Prepared Aconite Tuber
Patchouli oil
Probiotics
Passionfruit
Paeoniflorin
Poppy
Polygala
Petiveria
Plectranthus amboinicus
Purple Monkeyflower
Rue
Rosavins
Rauvolfia
Rosmarinic Acid
Rose
Rooibos
Sophora
Speedwell
Scoparia dulcis
Sete sangrias
Sesquiterpenes
Sumbul
Self-Heal
Spikenard
Scleranthus annus
Salvia
Sensitive Plant
Southern Tsangshu
Southernwood
Salidroside
Shankhpushpi
Schisandrins
Sandalwood
Stachytarpheta cayennensis
Schizandrol A
Storax
Saffranal
Sweet Orange alcohol
Terpenoids
Tea
Traveler's Joy
Trichilia catigua
Tagara
Tetrahydropalmatine
Uncaria
Vetiver
Valerenic acid
Vervain
Vitexin
Viburnum
Verbena
Violet
Vitex Agnus-Castus
Withanolides
White Tea
Wogonin
Xylaria nigripes
Yuzu
Yerba buena
yohimbine
Ylang ylang

Products containing Hemp

We currently have no products on Vitabase that contain this ingredient.